Abstract
Purpose :
It is well known that there is a high prevalence of vitreoretinal interface abnormalities, such as epiretinal membrane and incomplete vitreoretinal separation, in patients with diabetic retinopathy (DR). Xephilio OCT-S1 (Canon) can capture a swept source OCT image up to 23 mm with a single acquisition and is expected to provide detailed evaluation of the vitreoretinal interface over a wide field. We aimed to evaluate the vitreoretinal interface with wide-field OCT in eyes with DR.
Methods :
This cross-sectional study included 193 eyes of 112 patients (mean [SD] age, 63[12] years; 41 females, 71 males) with DR. All patients underwent 23 mm OCT imaging using OCT-S1 through the fovea, with the focus placed at -3.0 diopter to the vitreous cavity, to visualize the vitreoretinal interface in more detail. All eyes staged by diabetic retinopathy severity were classified into posterior vitreous detachment (PVD) stages and categorized by the presence or absence of vitreoretinal interface abnormalities.
Results :
The cohort of eyes with no DR (16 eyes; mean age: 68[14] years) consisted included seven eyes with stage 2 PVD, nine eyes with stage 4 PVD, and no eyes with vitreoretinal interface abnormalities. The eyes with non-proliferative diabetic retinopathy (NPDR; 81eyes; mean age: 65[11] years) included eight eyes with stage 0 PVD, 11 eyes with stage 1 PVD, 13 eyes with stage 2 PVD, six eyes with stage 3 PVD, and 43 eyes with stage 4 PVD. Of these, 23% had vitreoretinal interface abnormalities. The eyes with PDR (96 eyes; mean age: 59[11] years) included eight eyes with stage 0 PVD, seven eyes with stage 1 PVD, 21 eyes with stage 2 PVD, 24 eyes with stage 3, and 36 eyes with stage 4 PVD, of which 43% had vitreoretinal interface abnormalities.
Conclusions :
Although there was no significant difference in the composition of the PVD stage according to DR severity, the proportion of vitreoretinal interface abnormalities increased with severity.
This is a 2021 ARVO Annual Meeting abstract.