June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Association between myopiogenic factors and emmetropia in a Taiwan preschool population
Author Affiliations & Notes
  • Chiao Yu Wang
    National Yang Ming University Hospital, Ilan, Ilan, Taiwan
  • Nai-Wei Hsu
    Health Bureau, Yilan County Government, Yilan, Yilan, Taiwan
  • Yu-Chieh Yang
    Show Chwan Health Care System, Changhua, Changhua, Taiwan
  • Mong-Ping Shyong
    Suao Branch, Taipei Veterans General Hospital, Ilan, Taiwan
  • Der-Chong Tsai
    National Yang Ming University Hospital, Ilan, Ilan, Taiwan
  • Footnotes
    Commercial Relationships   Chiao Yu Wang, None; Nai-Wei Hsu, None; Yu-Chieh Yang, None; Mong-Ping Shyong, None; Der-Chong Tsai, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 2337. doi:
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      Chiao Yu Wang, Nai-Wei Hsu, Yu-Chieh Yang, Mong-Ping Shyong, Der-Chong Tsai; Association between myopiogenic factors and emmetropia in a Taiwan preschool population. Invest. Ophthalmol. Vis. Sci. 2021;62(8):2337.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Emmetropia has been reported as a predictor of myopia onset. But the distribution of myopiogenic factors among emmetropic children has not been well understood. This study aimed to investigate the factors for myopia among preschoolers and the associations with emmetropia.

Methods : Since launch of the Yilan Myopia Prevention and Vision Improvement Program (YMVIP) in August 2014, we have promoted outdoor activities and conducted a countywide population-based, annual cross-sectional study in all kindergartens in Yilan County, Taiwan. Eye examinations, including cycloplegic autorefraction, have been provided for all preschoolers aged 5-6 years. Demographics, medical history, parental history, near work habits, screen time and outdoor activity was collected by questionnaire. Refractive status was determined according to the cycloplegic spherical equivalent (SE) of the eye with less SE and classified into myopia (SE ≤-0.5D), emmetropia (0.5D > SE >-0.5D), or hyperopia (SE ≥0.5 D).

Results : Among 20,419 preschoolers from 2014 through 2019, a total of 18, 621 (9,715 [52.2%] boys) were finally included. Of those, 2,003 (10.8%), 5,057 (27.2%) and 11,561 (62.0%) were myopic, emmetropic and hyperopic. Most of association factors for myopia identified by multinomial logistic regression, including male (odds ratio [OR], 1.25; 95% CI, 1.13-1.37), caregiver myopia (OR, 1.76; 95% CI, 1.58-1.96), screen time ≥1 hour/weekday (OR, 1.20; 95% CI, 1.09-1.32), exposure to the YMVIP promoting outdoor activity (one-year exposure: OR, 0.80; 95% CI, 0.69-0.94; two-year exposure: OR, 0.46; 95% CI, 0.41-0.52), and higher education level of caregiver (OR, 0.79; 95% CI, 0.72-0.88), were also significantly associated with emmetropia (male [OR, 1.22; 95% CI, 1.14-1.30), caregiver myopia [OR, 1.42; 95% CI, 1.32-1.53], screen time ≥1 hour/weekday [OR, 1.15; 95% CI, 1.07-1.23], exposure to the YMVIP promoting outdoor activity [one-year exposure: OR, 0.84; 95% CI, 0.74-0.94; two-year exposure: OR, 0.62; 95% CI, 0.56-0.68], and higher education level of caregiver [OR, 0.87; 95% CI, 0.81-0.94]).

Conclusions : Emmetropia and myopia share similar risk factors in a preschooler population and the associations of these myopiogenic factors with emmetropia are weaker than with myopia, which may indicate the tendency of emmetropia toward myopia among preschoolers.

This is a 2021 ARVO Annual Meeting abstract.

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