June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Endophthalmitis, visual outcomes, and management strategies in eyes with intraocular foreign bodies
Author Affiliations & Notes
  • Jason Michael Keil
    Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, United States
  • Peter Yu Cheng Zhao
    Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, United States
  • Asad Farooq Durrani
    Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, United States
  • Lyna Azzouz
    Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, United States
  • Michael J Huvard
    Ophthalmology, University of Colorado Denver School of Medicine, Aurora, Colorado, United States
  • Vaidehi S Dedania
    Ophthalmology, NYU Langone Health, New York, New York, United States
  • David N Zacks
    Kellogg Eye Center, Department of Ophthalmology and Visual Sciences, University of Michigan Medical School, Ann Arbor, Michigan, United States
  • Footnotes
    Commercial Relationships   Jason Keil, None; Peter Zhao, None; Asad Durrani, None; Lyna Azzouz, None; Michael Huvard, None; Vaidehi Dedania, None; David Zacks, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 3679. doi:
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      Jason Michael Keil, Peter Yu Cheng Zhao, Asad Farooq Durrani, Lyna Azzouz, Michael J Huvard, Vaidehi S Dedania, David N Zacks; Endophthalmitis, visual outcomes, and management strategies in eyes with intraocular foreign bodies. Invest. Ophthalmol. Vis. Sci. 2021;62(8):3679.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To identify risk factors for endophthalmitis and poor visual outcomes in cases of retained intraocular foreign body (IOFB) and management strategies for these cases.

Methods : A retrospective chart review was conducted in 88 eyes of 88 patients suffering traumatic injury with retained IOFB at the University of Michigan between January 2000 and December 2019. Medical records were reviewed to identify the nature of the injury, IOFB composition, and presenting characteristics of each eye as well as the surgical and antimicrobial strategies employed. Details of the injury, IOFBs, and clinical presentation were utilized to identify factors associated with clinical outcomes. Visual outcomes and development of endophthalmitis were additionally evaluated for association with treatment modalities.

Results : This cohort developed endophthalmitis at a rate of 11.4% (4.5% presented with endophthalmitis, 7.1% of the remaining eyes developed endophthalmitis after initial intervention). Delayed presentation and organic IOFB were significantly associated with development of endophthalmitis. Retinal detachment, wound length greater than 5 mm, and poor presenting visual acuity were associated with poor final visual outcome. Antibiotic prophylaxis was given to all patients, though agents and routes of delivery varied. Primary and deferred removal of posterior segment IOFBs were associated with similar rates of endophthalmitis.

Conclusions : Poor presenting visual acuity and severity of injury as measured by large wound and retinal detachment correlate with poor visual outcome. Prompt globe closure and antimicrobial prophylaxis is critical for infection prevention. Deferred IOFB removal may carry similar risk of endophthalmitis as primary removal.

This is a 2021 ARVO Annual Meeting abstract.

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