June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Clinical characteristics and surgical outcomes of patients undergoing pars plana vitrectomy for complications of proliferative diabetic retinopathy
Author Affiliations & Notes
  • Tamara Ann Voor
    The University of Texas Southwestern Medical Center, Dallas, Texas, United States
  • Hank Patrick
    The University of Texas Southwestern Medical Center, Dallas, Texas, United States
  • Jessica Lee
    The University of Texas Southwestern Medical Center, Dallas, Texas, United States
  • Angeline Wang
    The University of Texas Southwestern Medical Center, Dallas, Texas, United States
  • Footnotes
    Commercial Relationships   Tamara Voor, None; Hank Patrick, None; Jessica Lee, None; Angeline Wang, None
  • Footnotes
    Support  NEI Core Grant P30 EY030413 and Research to Prevent Blindness
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 3672. doi:
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      Tamara Ann Voor, Hank Patrick, Jessica Lee, Angeline Wang; Clinical characteristics and surgical outcomes of patients undergoing pars plana vitrectomy for complications of proliferative diabetic retinopathy. Invest. Ophthalmol. Vis. Sci. 2021;62(8):3672.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To determine the outcomes of patients undergoing pars plana vitrectomy (PPV) surgery for complications of proliferative diabetic retinopathy (PDR).

Methods : Retrospective, observational chart review of 291 eyes of 217 patients that underwent PPV for complications of PDR at a large county hospital in Dallas, Texas from 2014 to 2019. Outcome measures included retinal re-attachment success rate, best-corrected visual acuity, and need for repeat PPV. Patients were excluded if they had less than 6 months of follow-up.

Results : Patients were 55.8% male and 44.2% female with an average age of 51 years (standard deviation (SD) of ± 9.5). Patients were followed for an average of 27.6 months, with a range of 6 to 71 months. The average Hgb A1c at time of surgery was 8.1 (SD ± 2.0). 72.3% of patients had their insurance covered by charity and 18.2% were covered by Medicaid/Medicare. 202 (93.1%) patients had other vascular risk factors or complications from diabetes, including hypertension (88.0%), hyperlipidemia (54.8%), chronic kidney disease (43.3%), need for dialysis (12.4%), coronary artery disease (8.8%), peripheral neuropathy (7.8%), need for amputation (7.4%), myocardial infarction (6.9%), and stroke (6.5%).

PPV surgery was performed for non-clearing vitreous hemorrhage in 110 eyes (37.8%), tractional retinal detachment (TRD) involving the macula in 98 eyes (33.7%), TRD not involving the macula in 50 eyes (17.2%), combined TRD and rhegmatogenous retinal detachment in 19 eyes (6.4%), and vitreomacular interface abnormalities in 14 eyes (4.7%). 81 eyes (27.8%) required gas tamponade and 29 eyes (10.0%) required silicone oil.

Average logMAR visual acuity was 1.75 (SD ± 0.74) pre-operatively and 0.92 (SD ± 0.87) at 1 year post-op. Retinal re-attachment success rate for patients with TRDs was 77.6% at 6 mo, 62.1% at 1 year, and 88.8% at most recent follow up. Common post-op complications included VH within 6 mos and cataracts. As of the most recent follow-up, 79 eyes (27%) needed repeat PPV and 91 (31.2%) needed cataract extraction (CE).

Conclusions : This study shows that vitrectomy is an overall safe and effective procedure that improves vision and stabilizes the retina in those with complications from PDR.

This is a 2021 ARVO Annual Meeting abstract.

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