June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Comparison of the quality of life between glaucoma and age-related macular degeneration patients living in a middle-income country.
Author Affiliations & Notes
  • Renato Maia Maccione
    Irmandade da Santa Casa de Misericordia de Sao Paulo, Sao Paulo, SP, Brazil
  • Kenzo S Tomishige
    Irmandade da Santa Casa de Misericordia de Sao Paulo, Sao Paulo, SP, Brazil
  • Caroline Schiave Germano
    Irmandade da Santa Casa de Misericordia de Sao Paulo, Sao Paulo, SP, Brazil
  • Patrícia Asperti Ottaiano
    Irmandade da Santa Casa de Misericordia de Sao Paulo, Sao Paulo, SP, Brazil
  • Niro Kasahara
    Irmandade da Santa Casa de Misericordia de Sao Paulo, Sao Paulo, SP, Brazil
  • Footnotes
    Commercial Relationships   Renato Maccione, None; Kenzo Tomishige, None; Caroline Germano, None; Patrícia Ottaiano, None; Niro Kasahara, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 3599. doi:
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      Renato Maia Maccione, Kenzo S Tomishige, Caroline Schiave Germano, Patrícia Asperti Ottaiano, Niro Kasahara; Comparison of the quality of life between glaucoma and age-related macular degeneration patients living in a middle-income country.. Invest. Ophthalmol. Vis. Sci. 2021;62(8):3599.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Health-related quality of life (QoL) has emerged as an essential health outcome in population health, clinical trials, and clinical improvement. Both patients with glaucoma and age-related macular degeneration (AMD) have compromised QoL as compared to their age-matched counterparts with normal vision. This topic has not been extensively assessed in patients with eye diseases living in low-middle income countries. This cross-sectional, case-control study aimed to compare the QoL between primary open-angle glaucoma (POAG) and AMD Brazilian patients.

Methods : Patients with AMD, POAG, and normal controls underwent a complete eye examination including measurement of best-corrected visual acuity, biomicroscopy, tonometry, and eye fundus evaluation; all participants answered the Brazilian-Portuguese version of the Visual Function Questionnaire 25 (VFQ-25). The VFQ-25 consists of a base set of 25 vision-target questions representing 11 vision-related constructs and one additional single-item general health rating question. Each item was scored and an overall composite score was calculated and compared among groups with the ANOVA test.

Results : The sample comprised 48 patients with AMD, 56 with POAG, and 53 controls. All groups were matched for age, gender, ethnic distribution, and comorbidites. VFQ-25 total score was lower in both POAG (61.8 ± 20.4) and AMD (50.7 ± 20.9) as compared to controls (89.3 ± 9.1, P<0.000); AMD patients’ score was lower than POAG patients (P = 0.04).

Conclusions : Brazilian patients with POAG and AMD presented significantly lower QoL highlighting the need to improve the care of patients in this middle-income country.

This is a 2021 ARVO Annual Meeting abstract.

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