June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
FREE DOWNLOADABLE APP TRACKS FUNCTIONAL GLAUCOMATOUS LOSS
Author Affiliations & Notes
  • Marium Sohail
    Columbia University Irving Medical Center, New York, New York, United States
  • Sitara Hanif Hirji
    Columbia University Irving Medical Center, New York, New York, United States
  • Jeffrey M Liebmann
    Columbia University Irving Medical Center, New York, New York, United States
  • George A Cioffi
    Columbia University Irving Medical Center, New York, New York, United States
  • Dana Blumberg
    Columbia University Irving Medical Center, New York, New York, United States
  • Footnotes
    Commercial Relationships   Marium Sohail, None; Sitara Hirji, None; Jeffrey Liebmann, None; George Cioffi, None; Dana Blumberg, None
  • Footnotes
    Support  NIH T-35 Ruth L. Kirschstein NRSA Short-Term Institutional Research Training Grant
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 3537. doi:
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      Marium Sohail, Sitara Hanif Hirji, Jeffrey M Liebmann, George A Cioffi, Dana Blumberg; FREE DOWNLOADABLE APP TRACKS FUNCTIONAL GLAUCOMATOUS LOSS. Invest. Ophthalmol. Vis. Sci. 2021;62(8):3537.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : In the covid crisis and beyond, it is critical that we find home-based monitoring tools to measure progressive glaucomatous damage. The primary purpose of this study is to examine the correlation between glaucomatous visual field loss and contrast sensitivity (CS) measured using a home based app.

Methods : 30 patients across the glaucomatous disease spectrum and with good central visual acuity tested a home based app, the Berkeley Contrast Squares (BCSA), that measures CS. The BCSA is a free-downloadable tool that records users’ binocular contrast sensitivity and is valid for varying degrees of visual acuity. Patients were sent a video (4min 46s) via email that contained detailed instructions on how to download and use the BCSA at home. The test-retest window was 15 weeks. Validity analyses was calculated using a mixed effects linear regression with log contrast sensitivity as the predictor and visual field as the outcome.

Results : In glaucoma patients the overall correlation for test-retest reliability was 0.94. Validity analyses showed high correlations between home-based contrast testing and 10-2 VF (p=0.002) and 24-2 VF (p=0.05). A change in 0.1 Log Weber corresponded to a 0.8 dB decline in 24-2 VF MD (95%CI [0.24 to 18.0]) ) and a 1.3 dB decline in 10-2 VF MD (95% CI [5.2 to 21.0]).

Conclusions : A free downloadable app provides a highly repeatable measure of CS. These results significantly correlate with functional visual field loss. This study suggests that the Berkeley Contrast Squares App has potential to be adopted as a home monitoring tool to track the progression of glaucoma between regular office visits.

This is a 2021 ARVO Annual Meeting abstract.

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