Investigative Ophthalmology & Visual Science Cover Image for Volume 62, Issue 8
June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Investigation of Visual Acuity and Amblyopia Changes in Preschoolers from UCLA’s Preschool Vision Program
Winnie Liu; Christina Le; J. Ben Margines; Fei Yu; Laura Syniuta; Bartly Mondino; Anne L Coleman; Simon Fung
Author Affiliations & Notes
  • Winnie Liu
    Department of Ophthalmology, University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States
    Jules Stein Eye Institute, Los Angeles, California, United States
  • Christina Le
    Department of Ophthalmology, University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States
    Jules Stein Eye Institute, Los Angeles, California, United States
  • J. Ben Margines
    Department of Ophthalmology, University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States
    Jules Stein Eye Institute, Los Angeles, California, United States
  • Fei Yu
    Jules Stein Eye Institute, Los Angeles, California, United States
    University of California Los Angeles Jonathan and Karin Fielding School of Public Health, Los Angeles, California, United States
  • Laura Syniuta
    Department of Ophthalmology, University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States
    Jules Stein Eye Institute, Los Angeles, California, United States
  • Bartly Mondino
    Department of Ophthalmology, University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States
    Jules Stein Eye Institute, Los Angeles, California, United States
  • Anne L Coleman
    Jules Stein Eye Institute, Los Angeles, California, United States
    University of California Los Angeles Jonathan and Karin Fielding School of Public Health, Los Angeles, California, United States
  • Simon Fung
    Department of Ophthalmology, University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, United States
    Jules Stein Eye Institute, Los Angeles, California, United States
  • Footnotes
    Commercial Relationships   Winnie Liu, None; Christina Le, None; J. Ben Margines, None; Fei Yu, None; Laura Syniuta, None; Bartly Mondino, None; Anne Coleman, None; Simon Fung, None
  • Footnotes
    Support  The authors thank and disclose funding from a grant from FIRST5LA. The research was also supported by an unrestricted grant from Research to Prevent Blindness (USA) to the UCLA Stein Eye Institute.
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 3491. doi:
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      Winnie Liu, Christina Le, J. Ben Margines, Fei Yu, Laura Syniuta, Bartly Mondino, Anne L Coleman, Simon Fung; Investigation of Visual Acuity and Amblyopia Changes in Preschoolers from UCLA’s Preschool Vision Program. Invest. Ophthalmol. Vis. Sci. 2021;62(8):3491.

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Abstract

Purpose : The UCLA Preschool Vision Program (UPVP) is a community outreach program that provided free on-site vision screenings and eyeglasses to Los Angeles preschoolers between 2012 – 2017. Here, we investigate the longitudinal visual outcome among those prescribed eyeglasses by UPVP.

Methods : This is a retrospective longitudinal case series. Preschoolers seen twice by UPVP were included. Study eye was designated as the eye with lower BCVA at initial visit. Data including best-corrected distance visual acuity (BCVA), refractive error, and severity of amblyopia were analyzed. Paired statistical analysis was performed using Wilcoxon signed rank and McNemar tests.

Results : 8,866 preschoolers were assessed twice by UPVP. 321 of them had a complete follow-up examination after being prescribed glasses. Mean(±standard deviation) BCVA at Visit 1 was 0.24±0.15 (95% CI: 0.23 to 0.26) logMAR, and 10.6% had unilateral amblyopia with mean BCVA of 0.43 ± 0.13 (95% CI: 0.37 to 0.49) logMAR. At 11.5±2.5 months, 52% of preschoolers wore glasses as prescribed at Visit 1. Follow-up mean BCVA was 0.16±0.12 logMAR (95% CI: 0.15 to 0.18) (p = 2.2 x 10-16). 88% of amblyopic preschoolers improved in BCVA, with mean change of 0.19±0.13 (95% CI: -0.24 to -0.15) logMAR (p = 2.51 x 10-6). BCVA change for glasses compliant amblyopia preschoolers was -0.23±0.12 (95% CI: -0.29 to -0.18) logMAR, while non-compliant group was -0.13±0.11 (95% CI: -0.20 to -0.05) logMAR (p = 0.025).

Conclusions : UPVP identified otherwise undetected vision deficiencies, such as amblyopia, and provided timely interventions to improve visual outcome. Compliance to prescribed glasses remains an obstacle to vision care.

This is a 2021 ARVO Annual Meeting abstract.

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
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Copyright © 2025 Association for Research in Vision and Ophthalmology.
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