June 2021
Volume 62, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2021
Racial Differences in Rhegmatogenous Retinal Detachment Repair Outcomes
Author Affiliations & Notes
  • Sarah Rahman
    School of Medicine, Case Western Reserve University, Cleveland, Ohio, United States
  • Neha Sharma
    School of Medicine, Case Western Reserve University, Cleveland, Ohio, United States
  • Victoria Blaga
    School of Medicine, Case Western Reserve University, Cleveland, Ohio, United States
  • Carolina C. S. Valentim
    Center for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • Rishi P. Singh
    Center for Ophthalmic Bioinformatics, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
    School of Medicine, Case Western Reserve University, Cleveland, Ohio, United States
  • Footnotes
    Commercial Relationships   Sarah Rahman, None; Neha Sharma, None; Victoria Blaga, None; Carolina Valentim, None; Rishi Singh, Alcon/Novartis (I), Apellis (F), Bausch + Lomb (I), Genentech/Roche (I), Graybug (F), Regeneron Pharmaceuticals, Inc. (I), Zeiss (I)
  • Footnotes
    Support  This study was supported in part by the NIH-NEI P30 Core Grant (IP30EY025585), Unrestricted Grants from The Research to Prevent Blindness, Inc., and Cleveland Eye Bank Foundation awarded to the Cole Eye Institute.
Investigative Ophthalmology & Visual Science June 2021, Vol.62, 3083. doi:
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      Sarah Rahman, Neha Sharma, Victoria Blaga, Carolina C. S. Valentim, Rishi P. Singh; Racial Differences in Rhegmatogenous Retinal Detachment Repair Outcomes. Invest. Ophthalmol. Vis. Sci. 2021;62(8):3083.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Rhegmatogenous Retinal Detachment (RRD) is a serious ocular condition that carries risk for vision loss. However, there remains a paucity of information on the impact of demographics on RRD repair outcomes. The purpose of this retrospective chart review is to characterize how RRD repair outcomes differ between racial groups.

Methods : Data was collected from electronic medical records of adult patients who underwent an RRD repair at Cole Eye Institute from 2012 to 2020. Patients were excluded if they had previous penetrating trauma to the presenting eye, previous posterior intraocular segment surgery to presenting eye, or less than 90 days of follow-up after surgery. Demographic differences were characterized. Univariate and multivariate logistic regression was used to compare retinal reattachment rate and macula-off status at diagnosis by race.

Results : Preliminary results are that 1012 patients underwent surgical RRD repair. Mean age of the patients was 63.8 years. 61.0% of the patients were male and 39.0% were female. 86.8% were white, 10.1% were black, 1.1% Asian and 2.1% other race. 95.1% of all patients, 95.6% of white patients, and 92.2% of black patients had successful retinal reattachment at 90 days following the procedure (p=0.162). Of patients who underwent one surgery, black patients had higher odds of repeat retinal detachment than white patients (OR 3.13, p=0.020, n=805), controlling for age, gender, and smoking status. Black patients also had higher odds of macula-off status at the time of diagnosis than white patients (OR 1.51, p=0.079, n=952). Current smokers have higher odds of macula-off status than non-smokers (OR 2.39, p=0.001, n=952).

Conclusions : Black patients have higher odds of their retina detaching after RRD repair when compared to white patients. There is also a trend for black patients to have relatively higher odds of macula-off detachment at presentation, however this is not statistically significant. This suggests that black patients may have both more severe presentation at diagnosis and worse outcomes of RRD surgical repair than white patients. Further studies are needed to determine factors that may mediate this association.

This is a 2021 ARVO Annual Meeting abstract.

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