August 2021
Volume 62, Issue 11
Open Access
ARVO Imaging in the Eye Conference Abstract  |   August 2021
Early Postoperative Central Macular Thickness Changes Following Uneventful Phacoemulsification Surgery
Author Affiliations & Notes
  • Mohamed M Khodeiry
    University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
  • Mohab Eldeeb
    University of Toronto, Toronto, Ontario, Canada
  • Mohamed S Sayed
    University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
  • Amr A Yazed
    Research Institute of Ophthalmology, Giza, Egypt
  • Esraa M Elkholy
    Research Institute of Ophthalmology, Giza, Egypt
  • Ebrahim S Elborgy
    Research Institute of Ophthalmology, Giza, Egypt
  • Footnotes
    Commercial Relationships   Mohamed Khodeiry, None; Mohab Eldeeb, None; Mohamed S Sayed, None; Amr Yazed, None; Esraa Elkholy, None; Ebrahim Elborgy, None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science August 2021, Vol.62, 6. doi:
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      Mohamed M Khodeiry, Mohab Eldeeb, Mohamed S Sayed, Amr A Yazed, Esraa M Elkholy, Ebrahim S Elborgy; Early Postoperative Central Macular Thickness Changes Following Uneventful Phacoemulsification Surgery. Invest. Ophthalmol. Vis. Sci. 2021;62(11):6.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate the effect of uneventful phacoemulsification on central macular thickness (CMT) using spectral-domain optical coherence tomography (SD-OCT) of the macula

Methods : A prospective non-comparative study including 30 eyes of 28 patients who underwent uneventful phacoemulsification surgery. Exclusion criteria included patients < 18 years, dense cataract or corneal opacity interfering with imaging, baseline macular pathologies i.e., diabetic macular edema (DME), age-related macular degeneration (AMD), and intraoperative posterior capsular rupture. Prior to surgery, all patients underwent a comprehensive ophthalmological exam and SD-OCT 6-×6-mm raster scan centered on the macular area (Heidelberg Engineering, Heidelberg, Germany). SD-OCT was repeated at 1-month and 3-month postoperative visits.

Results : The mean age of the patients was 58.57 ± 5.13 years. Nuclear cataract grade 2 was the most common cataract type in 24 eyes (80 %). Log MAR of visual acuity (VA) improved from 0.78 ± 0.26 to 0.14 ± 0.17 (p < 0.001). CMT changed from 260.40 ± 19.09 µm preoperatively to 279.00 ± 59.80 µm at month 1 (p = 0.043) and 265.40 ± 20.50 µm at month 3 (p=0.06) postoperatively. Effective phacoemulsification time (EPT) was 5.64 ± 1.24 seconds. A positive correlation was inferred between EPT and CMT change at month 1 (r=0.469, p = 0.009) and month 3 (r= 0.365, p= 0.048). None of the patients had clinically significant macular edema or decrease of VA related to macular edema.

Conclusions : A subclinical increase in CMT following uncomplicated phacoemulsification surgery was noted in the early postoperative period that could be due to surgical-induced inflammatory mediators release, mild intraoperative trauma from the surgery and fluidic changes, and the alteration of the vitreous position after the removal of the crystalline lens. Studies with a larger number of participants are needed to confirm our findings.

This is a 2021 Imaging in the Eye Conference abstract.

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