Abstract
Purpose :
To investigate choroidal features associated with non-ocular sarcoidosis using optical coherence tomography.
Methods :
In this retrospective case-control study, twenty eyes with non-ocular sarcoidosis and 20 age and spherical equivalent-matched healthy controls were evaluated. The subfoveal thickness, area ratio, and choroidal vascularity index (CVI) of the choroid were analyzed. Factors correlated with the choroidal thickness were investigated.
Results :
Sattler’s layer was significantly thicker in eyes with non-ocular sarcoidosis than in healthy controls, while there were no differences in Haller’s layer and total choroid between groups. The area ratio (Sattler’s to Haller’s layer) was also larger in eyes with non-ocular sarcoidosis than in control. There were no differences in terms of the CVIs of all sublayers between groups. Age was significantly associated with the thickness of Sattler’s layer.
Conclusions :
A disproportionate enlargement of subfoveal Sattler’s layer without vascular or total choroidal thickness changes may be subclinical manifestations of non-ocular sarcoidosis.
This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.