June 2022
Volume 63, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2022
Tear Exchange in Established Scleral Lens Wearers
Author Affiliations & Notes
  • Muriel Schornack
    Mayo Foundation for Medical Education and Research, Rochester, Minnesota, United States
  • Cherie B Nau
    Mayo Foundation for Medical Education and Research, Rochester, Minnesota, United States
  • Jennifer Harthan
    Illinois College of Optometry, Chicago, Illinois, United States
  • Ellen Shorter
    Illinois Eye and Ear Infirmary, Chicago, Illinois, United States
  • Amy Catherine Nau
    Korb and Associates, Boston, Massachusetts, United States
  • Kimberly Patton
    The Ohio State University, Columbus, Ohio, United States
  • Jennifer Fogt
    The Ohio State University, Columbus, Ohio, United States
  • Footnotes
    Commercial Relationships   Muriel Schornack None; Cherie Nau None; Jennifer Harthan Allergan, Essilor, Euclid Systems, International Keratoconus Academy, Metro Optics, SynergEyes, Visioneering Technologies, Inc., Code C (Consultant/Contractor), Bausch and Lomb, Kala Pharmaceuticals, Ocular Therapeutix, Metro Optics, Code F (Financial Support); Ellen Shorter Johnson & Johnson, BostonSight, Contamac, Art Optical, SynergEyes, Code F (Financial Support); Amy Nau None; Kimberly Patton None; Jennifer Fogt Alcon, Contamac, Code C (Consultant/Contractor), Nevakar, EyeNovia, Alcon, Innovega, Contamac, Code F (Financial Support)
  • Footnotes
    Support  National Center for Advancing Translational Sciences of the National Institutes of Health under grant: UL1TR002733. National Eye Institute Center Core Grant P30 EY001792hT. Research to Prevent Blindness.
Investigative Ophthalmology & Visual Science June 2022, Vol.63, 553 – A0251. doi:
  • Views
  • Share
  • Tools
    • Alerts
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Muriel Schornack, Cherie B Nau, Jennifer Harthan, Ellen Shorter, Amy Catherine Nau, Kimberly Patton, Jennifer Fogt; Tear Exchange in Established Scleral Lens Wearers. Invest. Ophthalmol. Vis. Sci. 2022;63(7):553 – A0251.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

  • Supplements

Purpose : Tear exchange beneath rigid contact lenses helps to supply the cornea with the oxygen required for normal corneal metabolism. Studies of short-term wear of scleral lenses (SLs) in healthy volunteers have suggested that minimal tear exchange occurs during SL wear. The purpose of the present study was to document tear exchange in established SL wearers.

Methods : Established SL wearers (≥ 6 months of wear) were recruited for this study during routine follow-up evaluations. All participants had worn their SLs for at least 2 hours prior to their study visits. Demographic data and landing zone (LZ) design for each lens was recorded. Sodium fluorescein (NaFl) was instilled over the lens in each eye. Presence or absence of NaFl in the post-lens fluid reservoir (FR) was recorded 10 seconds, 1 minute, 2.5 minutes, and 5 minutes after instillation. Differences between NaFl uptake into the FR between different lens designs and diameters were compared using Chi-squared tests.

Results : 30 established SL patients (53 eyes) with a were recruited (mean age of 46 ± 14.6 years (range 24-76)). Mean duration of lens wear prior to study visit was 4.8 ± 2.1 hours (range: 2.1-10 hours). Twenty-seven lenses (50%) had quadrant-specific LZ, 18 (34%) had toric LZ, and 8 had spherical LZ. Overall, NaFl was observed in the FR in 9 eyes (17%) at 10 seconds, 14 eyes (26.4%) at 1 minute, 25 eyes (47.2%) at 2.5 minutes, and 33 eyes (62.3%) at 5 minutes. With quadrant-specific LZ (n=25), NaFl was observed in the FR in 4 eyes (14.8%) at 10 seconds, 5 eyes (18.5%) at 1 minute, 11 eyes (40.7%) at 2.5 minutes, and 14 eyes (51.9%) at 5 minutes. With toric LZ (n=18), NaFl was observed in the FR in 3 eyes (16.7%) at 10 seconds, 7 eyes (38.9%) at 1 minute, 12 eyes (66.7%) at 2.5 minutes, and 15 eyes (83.3%) at 5 minutes. With spherical LZ (n=8), NaFl was observed in the FR in 2 eyes (25%) at 10 seconds, 1 minute, and 2.5 minutes and in 4 eyes (50%) at 5 minutes. No significant differences were noted between any LZ design at any time point (p=0.8, 10 seconds; p=0.3, 1 minute; p=0.08, 2.5 minutes; p= 0.09, 5 minutes).

Conclusions : Tear exchange occurs beneath SLs in a majority of established wearers. Neither lens diameter nor LZ design were associated with an increased likelihood of tear exchange in this sample.

This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.


This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.