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Hiroko Iwashita, Takashi Itokawa, Yukinobu Okajima, Takashi Suzuki, Yuichi Hori; Lubricating effect of three different eyedrops on contact lenses. Invest. Ophthalmol. Vis. Sci. 2022;63(7):524 – A0222.
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© ARVO (1962-2015); The Authors (2016-present)
Many Soft Contact lens (SCL) users medicate several eyedrops to improve discomforts. Friction of both SCL and ocular surface is one of important factor for CL discomfort. This study aimed to detect lubricating effect of three different eyedrops (artificial tears, low surface tension artificial tears, 0.1% hyaluronic acid) by measuring coefficient of friction (CoF).
The CoF was measured by using developed pendulum friction tester. The weight of the load was set at 17.2 g and estimated the pressure on the CL surface as 1.1 kPa. The maximal sliding velocity was set to 90.0 mm/s. Three daily disposable conventional hydrogel lenses (etafilcon A+ polyvinylpyrrolidone, nelfilcon A, and omafilcon A containing 2-methacryloyloxyethyl phosphorylcholine [MPC]) and four silicone hydrogel lenses (narafilcon A, senofilcon A, delefilcon A, and stenfilcon A) were measured under three different types of lubricants, artificial tears, lubricants containing 2-MPC (MPC solution) and 0.1% hyaluronic acid.
The mean ± SD of CoF of conventional hydrogel were Artificial tear; 0.038 ± 0.01, MPC solution; 0.036 ± 0.005, and 0.1% hyaluronic acid; 0.035 ± 0.005. Those of silicone hydrogel lenses were Artificial tear; 0.036 ± 0.004, MPC solution; 0.035 ± 0.003, and 0.1% hyaluronic acid; 0.036 ± 0.003. There were no significant differences of CoF among three lubricants and there was no significant difference of CoF between hydrogel and silicone hydrogel lenses. (P > 0.05).
Conclusions: Low surface tension artificial tears denotes high wettability on SCLs showed similar lubricate effect on SCLs as artificial tear and 0.1% hyaluronic acid. Three different eye drops showed similar lubricant effect on both conventional hydrogel and silicone hydrogel lenses. It was suggested that surface tension and viscosity of 0.1% HA on SCLs would not affect to CoF.
This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.
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