June 2022
Volume 63, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2022
OCT-based quantification of multifocal contact lenses on eye
Author Affiliations & Notes
  • Ana María González Ramos
    Consejo Superior de Investigaciones Cientificas, Madrid, Madrid, Spain
  • Shrilekha Vedhakrishnan
    Consejo Superior de Investigaciones Cientificas, Madrid, Madrid, Spain
  • Susana Marcos
    Consejo Superior de Investigaciones Cientificas, Madrid, Madrid, Spain
    Center for Visual Science, Rochester, New York, United States
  • Eduardo Martinez-Enriquez
    Consejo Superior de Investigaciones Cientificas, Madrid, Madrid, Spain
  • Footnotes
    Commercial Relationships   Ana María González Ramos None; Shrilekha Vedhakrishnan None; Susana Marcos WO2012146811A1, Code P (Patent); Eduardo Martinez-Enriquez None
  • Footnotes
    Support  Horizon 2020 European Project Imcustomeye (H2020-ICT-2017 Ref. 779960); Spanish Government FIS2017-84753-R , PID2020-115191RB-I00; NIH NIE P30EY 001319; Unrestricted Funds Research to Prevent Blindness, NY
Investigative Ophthalmology & Visual Science June 2022, Vol.63, 1817 – F0433. doi:
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    • Get Citation

      Ana María González Ramos, Shrilekha Vedhakrishnan, Susana Marcos, Eduardo Martinez-Enriquez; OCT-based quantification of multifocal contact lenses on eye. Invest. Ophthalmol. Vis. Sci. 2022;63(7):1817 – F0433.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Multifocal contact lenses (MCLs) are designed to provide near vision functionality in presbyopia. They rely on proper deployment of the multifocal power profile on the cornea and on optical interactions between the MCL and eye. Using custom-developed spectral Anterior Segment Optical Coherence Tomography (OCT) we evaluated the contact lens profile on eye, and potential conformity to the cornea.

Methods : OCT images were obtained on one eye of 13 subjects (age: 35.69 ± 13.83 y/o; Spherical error from -4.75D to +2.50D), with naked eyes and with MCLs on eye. All eyes were tested (5 repetitions) with the same MCLs: 1-Day Acuvue® Moist Brand MCL (Johnson & Johnson® Vision Care; -2.00D distance power; 8.4mm base curve; 14.3mm diameter) and three different additions: +1.25D (Low, L), +1.75D (Mid, M) and +2.50D (High, H). The OCT acquisition speed was 25000 A-Scans/s, the axial range was 7mm in depth, and the axial pixel size 3.4μm. Images were processed using custom routines for segmentation, fan distortion correction, 3D model construction, and surface fitting. The radius of curvature of the external surface of the MCLs (RCL) and the anterior surface of the naked cornea (RC) were obtained from spherical fitting within a 3-mm diameter central area (addition area) and within a 3-6 mm peripheral ring.

Results : RC ranged from 7.5 to 8.2 mm across subjects (8.02±0.22mm, on average). The shift in RCL in the periphery (by 0.55 mm on average) was consistent with the flattening produced by the negative MCL base power, and was constant independently of the corneal power of the subject. RC and RCL were correlated (p<<0.005) in the periphery for the three MCL additions (r=0.87, 0.84 and 0.82 for L, M and H adds, respectively) and also in the addition area (p<<0.005, r=0.85, 0.82, 0.78, L, M, H, respectively). The average RCL across subjects in the addition area was 8.37±0.31mm (L), 8.32±0.34mm (M) and 8.30±0.28 mm (H), and in the periphery was 8.59±0.30mm (L), 8.54±0.33mm (M) and 8.53±0.28mm (H), consistent with a relative central steepening, particularly for the higher add.

Conclusions : OCT provided with quantification tools allows to study the fitting of MCLs on eye in vivo. We found that, overall, soft MCLs conform to the underlying cornea, both in the central addition area and the periphery. However, the near central add is provided, as expected.

This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.

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