Abstract
Purpose :
Intraocular pressure (IOP) measurements, which can be affected by changes in corneal morphology, are used to screen and follow glaucoma. Riboflavin with ultraviolet-A-induced corneal collagen crosslinking (CXL) is used to treat keratoconus and also changes corneal morphology. The purpose of this study is to evaluate the effect of CXL on measured intraocular pressure.
Methods :
A retrospective chart review of 60 keratoconic human eyes, which underwent CXL, were included. Indentation (Tono-Pen: Reichert. Depew, NY USA) tonometry was used to evaluate IOP preoperatively and at one, three, and six-month post-CXL follow-up visits.
Results :
The average preoperative IOP was 14.1 +/- 2.1. The average IOP at the 1-month, 3-month, and 6-month follow-up were 17.1 +/- 2.7, 15.8 +/- 2.3, and 16.8 +/- 1.8 respectively. Relative to the preoperative IOP, the IOP at the 1-month, 3-month, and 6-month follow-up were statistically significantly higher.
Conclusions :
A statistically significant increase was noted in measured IOP by Tono-Pen after CXL for keratoconus, which is likely due to an increase in corneal rigidity after CXL.
This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.