Abstract
Purpose :
Previous studies have shown that ocular anatomy may differ amongst ethnic groups. However, there are limited data on ethnic differences in corneal pachymetry and anterior chamber dimension. This study utilizes Pentacam data to compare corneal pachymetry and anterior chamber dimension between Hispanic and non-Hispanic White groups.
Methods :
In this retrospective study, we analyzed Pentacam data from patients 50 years or older who underwent surgery for senile cataract. We included patients who were self-identified as Hispanic White or non-Hispanic White. Exclusion criteria included non-White race or multiethnic groups, history of surgery or trauma of cornea or anterior segment, or any abnormalities in these structures. The following parameters were compared between Hispanic Whites or non-Hispanic Whites: pupil center pachymetry, pachymetry at vertex, thinnest location, corneal volume, anterior chamber volume, and anterior chamber depth.
Results :
This study consisted of 200 patients, including 103 Hispanic White individuals and 97 non-Hispanic White individuals. The mean age was 69.9 ± 7.4 years (range, 50-88 years), and there were 68 men and 132 women. There was no significant difference between Hispanic White and non-Hispanic White groups regarding age. There were no statistically significant differences between these two groups regarding pupil center pachymetry (546.2 ± 35.6 µm vs 548.2 ± 34.6 µm, P= 0.85), pachymetry at vertex (546.5 ± 35.3 µm vs 549.2 ± 34.7 µm, P=0.69), thinnest location (541.3 ± 36.1 µm vs 544.0 ± 33.5 µm, P=0.58), or corneal volume (59.4 ± 4.0 mm3 vs 59.4 ± 3.8 mm3, P=0.98). However, there were significant differences between Hispanic White and non-Hispanic White groups regarding anterior chamber volume (130.0 ± 45.6 mm3 vs 146.6 ± 38.0 mm3, respectively, P<0.001) and anterior chamber depth (2.6 ± 0.5 mm vs 2.7 ± 0.4 mm, respectively, P=0.01).
Conclusions :
Although no significant differences exist in corneal pachymetry between Hispanic Whites and non-Hispanic Whites, anterior chamber depth and volume are significantly lower in Hispanic Whites compared with non-Hispanic Whites. Such anatomical differences should be considered during intraocular surgeries.
This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.