June 2022
Volume 63, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2022
Morphologic changes and sensitivity of the retina after photocoagulation with various levels of autofluorescence
Author Affiliations & Notes
  • Kentaro Nishida
    Osaka Daigaku Daigakuin Igakukei Kenkyuka Igakubu Igaku Senko, Suita, Osaka, Japan
  • Takashi Fujikado
    Osaka Daigaku Daigakuin Igakukei Kenkyuka Igakubu Igaku Senko, Suita, Osaka, Japan
  • Kohji Nishida
    Osaka Daigaku Daigakuin Igakukei Kenkyuka Igakubu Igaku Senko, Suita, Osaka, Japan
  • Footnotes
    Commercial Relationships   Kentaro Nishida None; Takashi Fujikado None; Kohji Nishida None
  • Footnotes
    Support  JSPS KAKENHI Grant Number 21K12809
Investigative Ophthalmology & Visual Science June 2022, Vol.63, 2211 – F0274. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Kentaro Nishida, Takashi Fujikado, Kohji Nishida; Morphologic changes and sensitivity of the retina after photocoagulation with various levels of autofluorescence. Invest. Ophthalmol. Vis. Sci. 2022;63(7):2211 – F0274.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : To investigate the correlation between the morphology, autofluorescence and sensitivity of photocoagulated lesions in patients with proliferative diabetic retinopathy (PDR) with good vision.

Methods : Patients with PDR (n=17) who visited Osaka University Hospital from April 2019 to October 2021 and underwent panretinal photocoagulation more than one year ago (BCVA≧0.8) were included. Maintenance of the circulation of photocoagulation scars was confirmed by optical coherence tomography (OCT) angiography (Angioplex Elite 9000), while autofluorescence of photocoagulated lesions were evaluated using ultra-widefield retinal imaging(Optos: TX-200). The scars were then classified according to levels of autofluorescence—group A for those with no autofluorescence, group B for those with remaining autofluorescence, and group C as control. OCT (Spectralis) was used to evaluate the ellipsoid zone (EZ) lines of the photocoagulated lesions.

Results : The retinal sensitivities of photocoagulated lesions were 3.3±5.0dB, 15.3±4.4dB and 21.8±2.4dB for groups A (n=35), B (n=37) and C (n=32), respectively, while the percentages of remaining EZ lines were 5.7%, 81.1% and 100%, respectively. There are significant statistical differences (P <0.05) in both the retinal sensitivities of photocoagulated lesions and the percentages of remaining EZ lines.

Conclusions : The photoreceptors in photocoagulated lesions with autofluorescence retain morphology and some function.

This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×