Abstract
Purpose :
To compare the visual performance of a non-tinted monofocal intraocular lens (IOL) (ZCB00) and a yellow-tinted monofocal IOL (ZCB00V) of the same material and basic design.
Methods :
We evaluated postoperative parameters at 10 weeks after the last surgery in cataract patients who underwent bilateral ZCB00 or ZCB00V implantation from January 4, 2011, to November 19, 2020, with the right and left lenses implanted within 3 months of each other. The study enrolled 2278 eyes of 1139 patients. A linear mixed-effects model using data for both eyes, with strict adjustments for sex, age, subjective refraction spherical equivalent, subjective refraction cylinder, corneal astigmatism, axial length, corneal higher-order aberrations, and pupil diameter, ensured statistical validity.
Results :
Contrast sensitivity with glare (6.3/4.0/0.7 degrees) were significantly better in the yellow-tinted group (p<0.00068, Wald test), and contrast sensitivity (4.0/2.5/1.6 degrees), contrast sensitivity with glare (2.5/1.6/1.0 degrees), the 25-item National Eye Institute Visual Function Questionnaire (VFQ-25) score for general health, and near spectacle independence were likely better in the yellow-tinted group (p<0.05, Wald test). Uncorrected intermediate/near visual acuity (UIVA/UNVA), corrected near visual acuity (CNVA), higher-order aberration (internal, scaled to a pupil size of 6 mm) (WF_6_post_I_Trefoil), the VFQ-25 scores for Role_Limitation, Mental_Health, Social_Function, Distance_Vision, Color_Vision, were likely better in the non-tinted group (p<0.05, Wald test).
Conclusions :
The two IOL groups had different characteristics in terms of UIVA/UNVA/CNVA, contrast sensitivity, contrast sensitivity with glare, the VFQ-25 scores, higher-order aberration, and near spectacle independence.
This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.