June 2022
Volume 63, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2022
Retinal detachment after keratoprosthesis implantation: risk factors and visual outcomes
Author Affiliations & Notes
  • Praruj Pant
    Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States
  • Cason Robbins
    Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States
  • Clayton Wisely
    Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States
  • Rami Gabriel
    Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States
  • Sharon Fekrat
    Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States
  • Footnotes
    Commercial Relationships   Praruj Pant None; Cason Robbins None; Clayton Wisely None; Rami Gabriel None; Sharon Fekrat None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2022, Vol.63, 3444 – F0344. doi:
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    • Get Citation

      Praruj Pant, Cason Robbins, Clayton Wisely, Rami Gabriel, Sharon Fekrat; Retinal detachment after keratoprosthesis implantation: risk factors and visual outcomes. Invest. Ophthalmol. Vis. Sci. 2022;63(7):3444 – F0344.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To compare eyes that developed a retinal detachment (RD) after keratoprosthesis (K-Pro) implantation to those that did not.

Methods : Retrospective review of patients who underwent K-Pro implantation at Duke Eye Center between 2009 and 2018. Demographics, past ocular history, surgical outcomes, and visual outcomes were collected at 3 months, 12 months, 24 months, and 36 months after K-Pro and compared between two cohorts: 1) eyes that developed RD after K-Pro and 2) eyes that did not develop RD after K-Pro.

Results : 87 eyes that underwent K-Pro implantation were identified - 14 of which developed RD after K-Pro and 73 which did not. There was no significant difference in the age, sex, or race of patients who did or did not develop RD after K-Pro. There was no difference in past ocular surgical history or indication for K-Pro between the patients who did and did not develop RD after K-Pro. Among the 14 eyes that developed RD after K-Pro, RD developed between 72 and 229 days postop. Eyes with RD after K-Pro were more likely to have had a pars plana vitrectomy (PPV) prior to, at the same time as, or after K-Pro but before RD (11/14, 78.6%) when compared to eyes which did not develop RD (35/73, 47.9%), p = 0.035. Additionally, patients who developed RD after K-Pro were significantly more likely to have had PPV and endophthalmitis (4/14, 29%) compared to eyes which did not develop RD (3/73, 4%), p = 0.002. There was no difference in mean visual acuity between groups at 3 months, 12 months, and 24 months after K-Pro. Eyes that developed RD after K-Pro had significantly lower visual acuity at 36 months (20/8000) vs eyes that did not (20/800), p = 0.036.

Conclusions : Endophthalmitis and history of PPV either before or after K-Pro are risk factors for the development of RD after K-Pro. Eyes with and without RD after K-Pro had similar visual outcomes at 24 months but not 36 months after K-Pro.

This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.

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