June 2022
Volume 63, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2022
Localization of the Internal Limiting Membrane Flap After Macular Hole Surgery
Author Affiliations & Notes
  • Christine Morozova
    Retina Vitreous Associates Medical Group, Los Angeles, California, United States
  • Andy Morozov
    Retina Vitreous Associates Medical Group, Los Angeles, California, United States
  • Dan Kamen
    Retina Vitreous Associates Medical Group, Los Angeles, California, United States
  • Jin Zhang
    Retina Associates, Tucson, Arizona, United States
  • Rossella Favale
    Department of Neurosciences and Sensory Organs, Universita degli Studi di Bari Aldo Moro, Bari, Puglia, Italy
  • Mark Walsh
    Retina Associates, Tucson, Arizona, United States
  • Francesco Boscia
    Department of Neurosciences and Sensory Organs, Universita degli Studi di Bari Aldo Moro, Bari, Puglia, Italy
  • David S Boyer
    Retina Vitreous Associates Medical Group, Los Angeles, California, United States
  • Homayoun Tabandeh
    Retina Vitreous Associates Medical Group, Los Angeles, California, United States
  • Footnotes
    Commercial Relationships   Christine Morozova None; Andy Morozov None; Dan Kamen None; Jin Zhang None; Rossella Favale None; Mark Walsh None; Francesco Boscia None; David Boyer None; Homayoun Tabandeh None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2022, Vol.63, 3404 – F0304. doi:
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      Christine Morozova, Andy Morozov, Dan Kamen, Jin Zhang, Rossella Favale, Mark Walsh, Francesco Boscia, David S Boyer, Homayoun Tabandeh; Localization of the Internal Limiting Membrane Flap After Macular Hole Surgery. Invest. Ophthalmol. Vis. Sci. 2022;63(7):3404 – F0304.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate the status of the internal limiting (ILM) flap following various ILM flap techniques for macular holes (MH).

Methods : Retrospective case series including eyes that underwent pars plana vitrectomy (PPV) and ILM flap for MH. The FLAP techniques included conventional ILM flap (C-ILM), temporal ILM flap (T-ILM), superior wide-base ILM flap transposition (SWIFT), and pedicle ILM flap (P-ILM). Postoperative imaging included ICG fluorescence imaging (ICG-FI) (Spectralis, Heidelberg Engineering Inc., Heidelberg, Germany) and optical coherence tomography (OCT).

Results : 49 eyes of 40 patients, mean age 68.3 years, with mean follow-up of 10.3 months were included in the study. Ten (20%) eyes were highly myopic, 22 (45%) eyes had chronic MH, and 7 (14%) eyes had history of prior MH surgery. The ILM flap technique included C-ILM / T-ILM (22 eyes), SWIFT (25 eyes), and P-ILM (2 eyes).
The MH closed in 46 (94%) eyes. ICG fluorescence attributable to ILM flap was detected in all eyes, however, in 3 eyes the flap borders were not discernable. The ILM flap covered the MH completely in 36 (75%) eyes, partially in 7 (15%) eyes, and provided no coverage in 5 (10%) eyes. In 1 eye it was not possible to ascertain coverage on ICG-FI or OCT. In the 2 eyes with P-ILM the ICG-FI showed a displaced flap with no coverage of the MH.
In cases with closed MH, OCT demonstrated intraretinal ILM fragments in 5 (23%) eye in I-ILM /T-ILM groups, and in none of the eyes in SWIFT or P-ILM group. Imaging with ICG-FI / OCT showed folding of the ILM flap in 14 (64%) eyes in I-ILM / T-ILM group, in 6 (24%) eyes in SWIFT /P-ILM group, and in 1 eye in P-ILM group.

Conclusions : ILM flap techniques are associated with a high MH closure rate and are useful in the management of MHs with high-risk characteristics. Postoperative multimodal imaging including ICG-FI and OCT indicates good coverage of the MH by the ILM flap in the majority of the cases.

This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.

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