Abstract
Purpose :
The hyper-parallel optical coherence tomography (HP-OCTTM; Cylite, Melbourne, Australia) is a novel platform that uses a light source-splitting micro-lens array to allow for the rapid capture of whole-eye volumetric scans and resulting biometry measurements, with minimal artifact from patient movement. In this pilot study we compared the HP-OCT with the Argos (Santec Corporation, Komaki, Japan) swept-source OCT biometer to compare biometry measurements in patients with mature cataracts.
Methods :
Patients with mature cataracts underwent 3 repeat measurements on both the HP-OCT and the Argos biometer. Axial length (AL), anterior chamber depth (ACD), central corneal thickness (CCT), lens thickness (LT), white-to-white distance (WTW), and mean keratometry (K) measurements were compared between the two biometers. Statistical analysis was performed using paired t-tests and Pearson’s correlation coefficient.
Results :
21 eyes of 17 patients were measured. Mean AL measured by HP-OCT was 24.61±1.54 mm and by Argos 24.59±1.49 mm (p=0.34), with r= 0.99 (p< 0.001). Mean keratometry values were also similar (p=0.21), measuring 43.20±1.94 diopters and 43.31±2.08 diopters for the HP-OCT and Argos, respectively (r=0.98, p<0.001). ACD was 3.21±0.43 mm (HP-OCT) and 3.33±0.37 mm (Argos), p < 0.002, with r=0.93 (p<0.0001). CCT was 514.22±48.71 μm (HP-OCT), and 511.31±47.80 μm (Argos), p=0.19, with r=0.98 (p<0.0001). LT was 4.65±0.42 mm (HP-OCT) and 4.75±0.40 mm (Argos), p <0.017, with r=0.91 (p<0.0001). WTW was 11.24±0.73 mm (HP-OCT) and 12.43±0.69 mm (Argos), p<0.0001, with r=0.44 (p=0.046).
Conclusions :
The HP-OCT and Argos biometers showed excellent correlation and similar measurements for axial length, mean keratometry, and CCT values. Statistically significant differences were seen in ACD, LT, and WTW measurements between the two biometers. Larger studies are necessary to further evaluate the agreement between the HP-OCT and Argos biometers.
This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.