June 2022
Volume 63, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2022
Long-term surgical outcomes of Glaucoma Drainage Implants in eyes with preoperative intraocular pressure less than 19
Author Affiliations & Notes
  • Shahin Hallaj
    Glaucoma Research Center, Wills Eye Hospital, Philadelphia, Pennsylvania, United States
  • Jae-Chiang Wong
    Glaucoma Research Center, Wills Eye Hospital, Philadelphia, Pennsylvania, United States
    Rowan University School of Osteopathic Medicine, Stratford, New Jersey, United States
  • Reza Razeghinejad
    Glaucoma Research Center, Wills Eye Hospital, Philadelphia, Pennsylvania, United States
    Thomas Jefferson University Sidney Kimmel Medical College, Philadelphia, Pennsylvania, United States
  • Aakriti Garg Garg Shukla
    Glaucoma Research Center, Wills Eye Hospital, Philadelphia, Pennsylvania, United States
    Thomas Jefferson University Sidney Kimmel Medical College, Philadelphia, Pennsylvania, United States
  • Natasha N Kolomeyer
    Glaucoma Research Center, Wills Eye Hospital, Philadelphia, Pennsylvania, United States
    Thomas Jefferson University Sidney Kimmel Medical College, Philadelphia, Pennsylvania, United States
  • Jonathan S Myers
    Glaucoma Research Center, Wills Eye Hospital, Philadelphia, Pennsylvania, United States
    Thomas Jefferson University Sidney Kimmel Medical College, Philadelphia, Pennsylvania, United States
  • Daniel Lee
    Glaucoma Research Center, Wills Eye Hospital, Philadelphia, Pennsylvania, United States
    Thomas Jefferson University Sidney Kimmel Medical College, Philadelphia, Pennsylvania, United States
  • Footnotes
    Commercial Relationships   Shahin Hallaj None; Jae-Chiang Wong None; Reza Razeghinejad None; Aakriti Garg Garg Shukla None; Natasha Kolomeyer None; Jonathan Myers None; Daniel Lee None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2022, Vol.63, 3713 – A0398. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Shahin Hallaj, Jae-Chiang Wong, Reza Razeghinejad, Aakriti Garg Garg Shukla, Natasha N Kolomeyer, Jonathan S Myers, Daniel Lee; Long-term surgical outcomes of Glaucoma Drainage Implants in eyes with preoperative intraocular pressure less than 19. Invest. Ophthalmol. Vis. Sci. 2022;63(7):3713 – A0398.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : To determine long-term surgical outcomes of Glaucoma Drainage Implants for patients with low to normal preoperative intraocular pressures

Methods : The retrospective cohort study included patients requiring Glaucoma Drainage Implants (GDI) with preoperative Intraocular Pressures (IOP) less than 19 mmHg from March 2006 to May 2017. Patients with at least 1-year follow-up in the post-operative period were included. Demographic and clinical data were collected at the preoperative and postoperative visits for up to 7 years. Surgical failures were defined as eyes that required reoperation or progressed to no light perception

Results : 46 eyes of 45 patients met inclusion criteria. Mean patient age was 66.5±13.2 years old, and mean follow-up duration was 37.3±26.5 months (range: 12-84). 9 (18.7%) eyes experienced surgical complications: 3 (33%) inflammation, 3 (33%) flat anterior chamber, 1 (11%) hypotony (without any hypotony maculopathy), 1 (11%) exotropia/hypertropia. Among all 46 eyes included, 13 (28.2%) faced failure, all of which were due to the need for reoperation and revision (n=12, 92.3%) or removal (n=1, 7.6%) of the tube shunt. Unlike SLT, ALT, CPC, vitreoretinal, and corneal surgeries, a history of a previous trabeculectomy was significantly associated with a higher risk of failure (OR:3.938, p=0.046). Moreover, those with a higher MD/year loss rate had greater chances to experience GDI failure (p=0.036). Mean IOP ranged from 13.3±3.2 to 14.9±4.5 mmHg at the preoperative visit and each follow-up visit for up to 5 years (p>0.05 for all), respectively. Humphery 24-2 visual field (VF) mean deviations (n=11) were not significantly different at -11.8±10.2 and -15.9±5.8 (p>0.05) during the most recent preoperative and postoperative visits, respectively. Moreover, the mean annual progression rate was different at -2.6±2.0 and 0.23±0.67 for preoperative and postoperative VF loss (p=0.007), indicating that the intervention slowed down the pace of VF loss at 0.53 ± 1.4 MD/year. Nonetheless, the total number of medications used by the patients significantly reduced from 3.1 ± 3.5 preoperative to 1.7 ± 1.1one year postoperative (p=0.036).

Conclusions : Unchanged IOP, as well as slower postoperative mean VF loss progression rate reported in this study, implies the significant effectiveness of tube shunt placement in controlling glaucoma in patients with low to normal IOP.

This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×