Abstract
Purpose :
To evaluate the effect of combined phacoemulsification with Ahmed glaucoma valve implantation and combined phacoemulsification with Xen gel stent implantation on intraocular pressure (IOP) of patients with primary open angle glaucoma (POAG)
Methods :
In this retrospective study, we enrolled 12 patients who underwent combined phacoemulsification with Ahmed glaucoma valve implantation (group 1) and 15 patients who underwent combined phacoemulsification with Xen Gel stent implantation (group 2). All 27 patients had preoperative IOP of 18 mm Hg or higher. We compared the IOP and number of IOP-lowering medications at baseline and postoperative month 3 (POM3) between the two groups.
Results :
The age mean +/- standard deviation (SD) was 64.08+/-13.50 years for group 1 and 65.53+/-9.73 for group 2. Male composed 58% in group 1 and 60% in group 2. White gender composed 41.7% and 46.7% in group 1 and 2, respectively. After confirming the normality assumption, two sample t-test was performed for the difference between the two groups. At POM3, mean IOP decreased to 14.33+/-3.45 mm Hg (44% decrease) in group 1 and 18.53+/-8.38 (26.8% decrease) in group 2 (P=0.11). The number of IOP-lowering medications decreased from 3.08+/-0.90 to 1.33+/-1.16 in group 1, and from 3.13+/-1.30 to 1.27+/-1.39 in group 2 at POM3 visit (P=0.91).
Conclusions :
In this study, phacoemulsification combined with Ahmed glaucoma valve implantation was more effective at lowering IOP in comparison to phacoemulsification combined with Xen gel stent implantation, although this difference did not reach a statistically significance level. Further studies with a larger sample size might be able to show a statistically significant difference between the two procedures.
This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.