June 2022
Volume 63, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2022
Fellow eye comparison between Tanito microhook ab-interno trabeculotomy and iStent implantation combined with cataract surgery
Author Affiliations & Notes
  • Yuji Takayanagi
    Department of Ophthalmology, Shimane University Faculty of Medicine, Japan
  • Sho Ichioka
    Department of Ophthalmology, Shimane University Faculty of Medicine, Japan
  • Akiko Ishida
    Department of Ophthalmology, Shimane University Faculty of Medicine, Japan
  • Aika Tsutsui
    Department of Ophthalmology, Shimane University Faculty of Medicine, Japan
  • Masaki Tanito
    Department of Ophthalmology, Shimane University Faculty of Medicine, Japan
  • Footnotes
    Commercial Relationships   Yuji Takayanagi None; Sho Ichioka None; Akiko Ishida None; Aika Tsutsui None; Masaki Tanito Inami Co. Ltd., Code C (Consultant/Contractor), Inami Co. Ltd., Code P (Patent), Inami Co. Ltd., Code R (Recipient)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2022, Vol.63, 3683 – A0368. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Yuji Takayanagi, Sho Ichioka, Akiko Ishida, Aika Tsutsui, Masaki Tanito; Fellow eye comparison between Tanito microhook ab-interno trabeculotomy and iStent implantation combined with cataract surgery. Invest. Ophthalmol. Vis. Sci. 2022;63(7):3683 – A0368.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : The aim of this study was to compare the efficacy and complications after Tanito microhook ab-interno trabeculotomy (TMH) combined with cataract surgery in one eye and iStent implantation combined with cataract surgery in the fellow eye of a patient.

Methods : Sixty-four eyes of 32 participants (mean age, 75.9 ± 7.6 years; 15 men, 17 women) with primary-open angle glaucoma (65.6 %), exfoliation glaucoma (23.4 %), and other glaucoma types (11.0 %) were included retrospectively. The intraocular pressure (IOP) and number of antiglaucoma medications evaluated preoperatively and postoperatively at 2 weeks, 3, 6, and 12 months were collected by chart review. The postoperative complications including layered hyphema and IOP spike of 30 mmHg or higher also were collected. Comparisons between the two surgical procedures were performed by mixed-effects regression models and followed by Wilcoxon signed-rank test or Fisher’s exact probability test.

Results : The preoperative IOP and medications of TMH group (18.8 ± 5.7 mmHg and 3.0 ± 1.2 medications, respectively) were higher than those of iStent group (15.5 ± 3.4 mmHg and 2.7 ± 1.2 medications, respectively) (p<0.0001 and p=0.0437, respectively); while those of TMH group (12.6 ± 2.3 mmHg and 2.3 ± 0.9 medications, respectively) were identical to those of iStent group (12.8 ± 2.5 mmHg and 2.3 ± 0.9 medications, respectively) (p=0.0934 and p=0.3251, respectively) at the 12 months postoperatively. By mixed-effects regression analysis, postoperative reduction of IOP and medications were significantly different between the two groups (p<0.0001, p<0.0001, respectively). At 12 months postoperatively, reduction of IOP in TMH group (6.2 ± 5.6 mmHg, 29.5%) was greater than those in iStent group (2.7 ± 3.2 mmHg, 18.8%) (p=0.0003); reduction of medication in TMH group (0.7 ± 1.3, 23.3%) was greater than those of iStent group (0.4 ± 1.1, 14.8%) (p=0.0437). Frequency of layered hyphema were significantly higher in TMH group (8 eyes, 25%) than iStent group (0 eye, 0%) (p=0.0048); frequency of IOP spike was equivalent between the groups (TMH, 2 eyes, 6%; and iStent, 2 eyes, 6%) (p=1.0000).

Conclusions : By fellow-eye comparison, IOP reduction was greater with TMH than with iStent, while achieved levels of IOP was identical between both procedures. The rate of layered hyphema was higher in TMH than iStent.

This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×