Investigative Ophthalmology & Visual Science Cover Image for Volume 63, Issue 7
June 2022
Volume 63, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2022
Identifying the Greatest Barriers and Challenges in Performing Successful Corneal Transplantation in India
Author Affiliations & Notes
  • Priyanka Ramulu
    River Hill High School, Clarksville, Maryland, United States
  • Priya Mathews
    Johns Hopkins Medicine Wilmer Eye Institute, Baltimore, Maryland, United States
    Florida Eye Specialists and Cataract Institute, Florida, United States
  • Gavin Li
    Johns Hopkins Medicine Wilmer Eye Institute, Baltimore, Maryland, United States
  • David Cui
    Johns Hopkins Medicine Wilmer Eye Institute, Baltimore, Maryland, United States
  • Rajesh Fogla
    Apollo Specialty Hospitals Pvt Ltd, Hyderabad, India
  • Esen K Akpek
    Johns Hopkins Medicine Wilmer Eye Institute, Baltimore, Maryland, United States
  • Footnotes
    Commercial Relationships   Priyanka Ramulu None; Priya Mathews Dompe, Code C (Consultant/Contractor), SUN Pharmaceutical, Code C (Consultant/Contractor), W.L. Gore, Inc., Code C (Consultant/Contractor); Gavin Li None; David Cui None; Rajesh Fogla None; Esen Akpek Dompe, Epitech, FirstString Medical Research, Novalique, Shire, Sinqi, HanAll, Adelphi Values, Regeneron Healthcare Solutions Inc., Sjogren's Foundation, Code C (Consultant/Contractor), Novartis, Ocular Therapeutics, W.L. Gore, Inc, Regeneron Healthcare Solutions Inc., National Eye Institute, Code F (Financial Support), Up-To-date, Code P (Patent)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2022, Vol.63, 3539 – A0119. doi:
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      Priyanka Ramulu, Priya Mathews, Gavin Li, David Cui, Rajesh Fogla, Esen K Akpek; Identifying the Greatest Barriers and Challenges in Performing Successful Corneal Transplantation in India. Invest. Ophthalmol. Vis. Sci. 2022;63(7):3539 – A0119.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Currently, an estimated 1 in 70 individuals worldwide in need of a corneal transplant will actually undergo corneal transplantation. There is a lack of objective data explaining the underlying reasons for why this discrepancy exists. The purpose of this study was to use a newly developed questionnaire to identify the barriers for successfully performing corneal transplantation in India.

Methods : An online survey was sent to approximately 700 currently-practicing corneal specialists who were members of the Cornea Society of India. Members were invited to complete an online survey between January 1 and July 1, 2021. The survey asked the participants to rate the difficulty or ease of 11 steps of corneal transplantation using a Likert scale. Categories included factors related to donors, organ procurement, tissue
harvesting/storage, logistical, physician/staff/facility related, and recipient related.

Results : A total of 148 individuals participated in the online survey (~21% response rate). Of the 11 evaluated steps, the greatest barrier to transplantation was the difficulty in finding donors who fulfilled the screening criteria (55% of respondents reported difficulty). The second greatest barrier was donor willingness to donate (32% of respondents reported difficulty). Lastly, the third most reported barrier was the ability to store tissue after it was prepared by the eye bank (20% of respondents reported difficulty). The two steps with the least reported difficulty were availability of operating room (OR) time and staff, as well as using prepared corneal tissue before the expiration date.

Conclusions : There is a significant shortage of corneal transplants performed around the world, however there has never been a standardized way of identifying forces driving this shortage. Our online survey evaluated each step needed to successfully perform corneal transplantation. In India, it appears that the donor-related factors (both fulfilling donor criteria and patient/family willingness to donate) and ability to store prepared tissue were the greatest barriers in performing corneal transplantation. Therefore, both government and private institutions should focus their resources and efforts on addressing these issues to ultimately reduce the burden of corneal blindness.

This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.

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