Abstract
Purpose :
Purpose: To describe the long-term safety, intraocular pressure (IOP) lowering effect, and reduced surgical burden of the Kahook Dual Blade® (New World Medical, Rancho Cucamonga, California) as a standalone procedure when used to excise trabecular meshwork in eyes with primary open angle glaucoma (POAG).
Methods :
Methods: This is a retrospective chart review of 39 eyes from 2 sites in the United States that included data collection of IOP, IOP-lowering medications, and additional glaucoma procedures at months 12, 24, 36, and 48. Eyes were not washed out of their previous IOP-lowering medications for this analysis. Intra- and postoperative adverse events were tabulated
Results :
Results: Analysis from 39 eyes showed a mean IOP reduction from a baseline of 20.4 to 15.0 mmHg at month 48 (26.4% reduction, p < 0.001) Medication use at 48 months was similar to baseline (p=0.123). 33/39 (85%) eyes required no further surgery to manage IOP. One case of mild iritis related to the procedure was reported.
Conclusions :
Conclusion: Excisional goniotomy with KDB effectively decreases IOP over long-term follow up when utilized as a standalone procedure in eyes with POAG. The device also shows a favorable safety profile in line with other minimally invasive glaucoma surgical interventions. Notably, the vast majority of patients (85%) did not require additional surgical intervention to further lower IOP for the duration of the study.
This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.