Investigative Ophthalmology & Visual Science Cover Image for Volume 63, Issue 7
June 2022
Volume 63, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2022
Higher rates of strabismus surgery and residual amblyopia in children with Medicaid using the IRIS Registry
Author Affiliations & Notes
  • Marian S. Blazes
    Ophthalmology, University of Washington, Seattle, Washington, United States
  • Megan Lacy
    Ophthalmology, University of Washington, Seattle, Washington, United States
  • Aaron Y Lee
    Ophthalmology, University of Washington, Seattle, Washington, United States
  • Cecilia S Lee
    Ophthalmology, University of Washington, Seattle, Washington, United States
  • Kristina Tarczy-Hornoch
    Ophthalmology, University of Washington, Seattle, Washington, United States
    Seattle Children's Hospital, Seattle, Washington, United States
  • Footnotes
    Commercial Relationships   Marian Blazes None; Megan Lacy None; Aaron Lee Genentech, Verana Health, Johnson and Johnson, Gyroscope, Code C (Consultant/Contractor), US Food and Drug Administration, Code E (Employment), Santen, Carl Zeiss Meditec, Novartis, Microsoft, NVIDIA, Code F (Financial Support), Topcon, Code R (Recipient); Cecilia Lee None; Kristina Tarczy-Hornoch None
  • Footnotes
    Support  NIH/NIA R01AG060942 (Cecilia S. Lee), NIH/NEI K23EY029246 (Aaron Y. Lee), NIH/NIA U19AG066567 (Cecilia S. Lee and Aaron Y. Lee), the Latham Vision Grant (Cecilia S. Lee and Aaron Y. Lee), an unrestricted core grant from Research to Prevent Blindness (Cecilia S. Lee and Aaron Y. Lee), and the Keralis Johnson Retina Center (Cecilia S. Lee and Aaron Y. Lee).
Investigative Ophthalmology & Visual Science June 2022, Vol.63, 3659 – A0316. doi:
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    • Get Citation

      Marian S. Blazes, Megan Lacy, Aaron Y Lee, Cecilia S Lee, Kristina Tarczy-Hornoch; Higher rates of strabismus surgery and residual amblyopia in children with Medicaid using the IRIS Registry. Invest. Ophthalmol. Vis. Sci. 2022;63(7):3659 – A0316.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose :
Timely strabismus diagnosis may improve amblyopia outcomes or prevent need for surgery. We assessed factors associated with delayed diagnoses and worse outcomes in pediatric strabismus.

Methods : We analyzed electronic health record data from the American Academy of Ophthalmology IRIS® Registry (Intelligent Research in Sight), including children ≤10 years with exotropia or esotropia diagnosis codes. Primary outcome was age at strabismus diagnosis. Associations between strabismus surgery or residual amblyopia and race/ethnicity, insurance, population density, and access to pediatric ophthalmology were analyzed using multivariable linear, logistic regression, and survival analysis.

Results :
Of 161,600 children with new diagnosis of esotropia (107,005) or exotropia (54,595), 43.5% were diagnosed before age of 4. Esotropic Hispanic, Black, and Asian children were diagnosed an average of 5.2 (95% CI: 2.8, 7.5),14.1 (11.2, 17.1) and 8.2 (3.2,13.3) weeks earlier compared to White children, and those with Medicaid were diagnosed 9.5 (7.9,11.2) weeks earlier compared to those with commercial insurance. Exotropic Hispanic and Asian children were diagnosed 10.6 (7.4, 13.8) and 40.9 weeks (35.3, 46.6) later than White children, and Medicaid patients (vs. commercial insurance) 12 weeks earlier (9.5, 14.4). The hazard ratio of strabismus surgery for Medicaid vs. commercial insurance was 1.28 (1.23, 1.32) for esotropia and 1.22 (1.17, 1.27) for exotropia.(Figure) Odds of developing residual amblyopia were significantly higher in children with Medicaid vs. commercial insurance both for esotropia [OR 1.75; 95%CI 1.68, 1.8] and exotropia (1.57; 1.46, 1.69).(Table) Controlling for age of strabismus diagnosis had minimal impact on our results.

Conclusions :
Strabismic children with Medicaid did not appear to have a delayed diagnosis yet were more likely to require surgery and develop residual amblyopia.

This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.

 


Multivariable logistic regression model of impact of covariates on odds of residual amblyopia as measured by a discrepancy in logmar visual acuity ≥ 0.2 after age 8 in participants who had a visit after age 8.


Multivariable logistic regression model of impact of covariates on odds of residual amblyopia as measured by a discrepancy in logmar visual acuity ≥ 0.2 after age 8 in participants who had a visit after age 8.

 


Time to surgery Kaplan Meier curves. x-axis: days from strabismus diagnosis, y-axis: probability of not having surgery. Red, commercial insurance; green: Medicaid.


Time to surgery Kaplan Meier curves. x-axis: days from strabismus diagnosis, y-axis: probability of not having surgery. Red, commercial insurance; green: Medicaid.

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