June 2022
Volume 63, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2022
Assessing Usability and Clinical Utility of GLANCE, an Artificial Intelligence-based Tool for Predicting Glaucoma Visual Field Progression
Author Affiliations & Notes
  • Alexander Lieu
    Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, La Jolla, California, United States
  • Astrid van den Brandt
    Technische Universiteit Eindhoven, Eindhoven, Noord-Brabant, Netherlands
  • Mark Christopher
    Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, La Jolla, California, United States
  • Derek Stuart Welsbie
    Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, La Jolla, California, United States
  • Jiun Lap Do
    Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, La Jolla, California, United States
  • Andrew Camp
    Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, La Jolla, California, United States
  • Sasan Moghimi
    Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, La Jolla, California, United States
  • Sally Liu Baxter
    Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, La Jolla, California, United States
    Health Department of Biomedical Informatics, University of California San Diego, La Jolla, California, United States
  • Linda M Zangwill
    Viterbi Family Department of Ophthalmology and Shiley Eye Institute, University of California San Diego, La Jolla, California, United States
  • Footnotes
    Commercial Relationships   Alexander Lieu None; Astrid van den Brandt None; Mark Christopher None; Derek Welsbie Perceive Biotherapeutics, Code C (Consultant/Contractor); Jiun Do VoxelCloud, Nicox, Code C (Consultant/Contractor); Andrew Camp None; Sasan Moghimi None; Sally Baxter None; Linda Zangwill Abbvie Inc., Digital Diagnostics, Code C (Consultant/Contractor), Carl Zeiss Meditec Inc., Heidelberg Engineering GmbH, Optovue Inc., Topcon Medical Systems Inc., Code F (Financial Support), Zeiss Meditec, Code P (Patent)
  • Footnotes
    Support  DP5OD029610 (NIH), P30EY022589 (NIH/NEI), Unrestricted departmental grant from Research to Prevent Blindness
Investigative Ophthalmology & Visual Science June 2022, Vol.63, 2008 – A0449. doi:
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    • Get Citation

      Alexander Lieu, Astrid van den Brandt, Mark Christopher, Derek Stuart Welsbie, Jiun Lap Do, Andrew Camp, Sasan Moghimi, Sally Liu Baxter, Linda M Zangwill; Assessing Usability and Clinical Utility of GLANCE, an Artificial Intelligence-based Tool for Predicting Glaucoma Visual Field Progression. Invest. Ophthalmol. Vis. Sci. 2022;63(7):2008 – A0449.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Artificial intelligence (AI) has the potential to improve risk stratification in glaucoma, but interface design and usability of AI-based clinical decision support tools have been understudied. GLANCE is a visualization tool depicting predicted mean deviation of visual fields (VFs) based on a deep learning model trained on optical coherence tomography (OCT) images, with the potential to reduce VF testing frequency (van den Brandt A, et al., Eurographics Workshop on Visual Computing for Biology and Medicine, 2020). Here, we conducted a pilot study of clinicians using an updated prototype of GLANCE to assess usability, trust in the tool, and utility for clinical management.

Methods : Our updated prototype of GLANCE included dynamic visualization of the AI model output (predicted VF mean deviation) alongside prior VFs and model predictions, intraocular pressure measurements, and clinical history (Fig.1). An online survey consisting of six patient cases with the GLANCE tool was disseminated to clinicians at the University of California San Diego. Participants were asked to comment on whether GLANCE provided additional useful information and whether it impacted their clinical management using 5-point Likert scale items (Fig. 2). They also completed a System Usability Scale (SUS) questionnaire, a standardized instrument for assessing usability.

Results : Seven clinicians (two attendings, two fellows, two residents, and one optometrist) participated in the pilot. The mean SUS score of GLANCE was 62.5/100, which is normalized into the 35th percentile. The mean SUS score among respondents ages 35-44 (75) was greater than ages 65-74 (45). The mean score among female respondents (67.5) was greater than male respondents (57.5). Respondents generally agreed that they trusted GLANCE and that it provided useful information, but disagreed that they would decrease VF testing frequency (Fig.2).

Conclusions : Clinicians agreed that GLANCE provided useful information but were generally not yet willing to allow AI tools to significantly alter their clinical management. Further research is needed to understand how to increase trust in AI models, improve the usability of visualization tools and interfaces, and optimize the integration of AI-based tools into ophthalmic workflows among a diverse group of clinicians.

This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.

 

GLANCE tool for an example case.

GLANCE tool for an example case.

 

Clinician perceptions of GLANCE.

Clinician perceptions of GLANCE.

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