Abstract
Purpose :
To describe the corneal and refractive properties of patients with congenital nystagmus syndrome compared to healthy subjects.
Methods :
In this comparative cross-sectional observational study, a scheimpflug imaging tomography was conducted on eyes of congenital nystagmus syndrome patients and compared with those of healthy individuals (control group). Corneal astigmatism prevalence, corneal astigmatic power, maximal keratometry, mean keratometry and pachymetry values were obtained and compared between the groups.
Results :
32 eyes of 16 congenital nystagmus syndrome patients and 32 eyes of 16 healthy individuals were included in the study. All nystagmus patients (100%) had astigmatism of at least 1 diopter compared to 11 subjects (34.375%) in the control group (P<0.001). The average astigmatic power in the patient’s group was 3.383 ± 1.135 diopters compared to 0.8281 ± 0.58.54 diopters in the control group (P<0.001). The maximal keratometric power in the patient’s group was 44.16 ± 2.444 diopters compared to 42.88 ± 2.052 diopters in the control group (P=0.027). The mean keratometric power in the patient’s group was 41.98 ± 2.129 diopters compared to 41.40 ± 5.121 diopters in the control group (P=0.560). The mean pachymetric value in the patient’s group was 557.1 ± 47.15 µm compared to 544.2 ± 29.32 µm in the control group (P=0.1945).
Conclusions :
All patients with congenital nystagmus syndrome have visually significant astigmatism. Corneal tomography can be used to asses and grade the corneal astigmatism in these patients.
This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.