June 2022
Volume 63, Issue 7
Open Access
ARVO Annual Meeting Abstract  |   June 2022
Assessment of crystalline lens shape during accommodation using IOLMaster 700 B-scan images
Asik Pradhan; Rohan Hughes; Emily Pieterse; David Andrew Atchison; Stephen Vincent; Scott Read; Andrew Carkeet
Author Affiliations & Notes
  • Asik Pradhan
    Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia
    Centre for Vision and Eye Research, Queensland University of Technology, Brisbane, Queensland, Australia
  • Rohan Hughes
    Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia
    Centre for Vision and Eye Research, Queensland University of Technology, Brisbane, Queensland, Australia
  • Emily Pieterse
    Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia
    Centre for Vision and Eye Research, Queensland University of Technology, Brisbane, Queensland, Australia
  • David Andrew Atchison
    Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia
    Centre for Vision and Eye Research, Queensland University of Technology, Brisbane, Queensland, Australia
  • Stephen Vincent
    Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia
    Centre for Vision and Eye Research, Queensland University of Technology, Brisbane, Queensland, Australia
  • Scott Read
    Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia
    Centre for Vision and Eye Research, Queensland University of Technology, Brisbane, Queensland, Australia
  • Andrew Carkeet
    Optometry and Vision Science, Queensland University of Technology, Brisbane, Queensland, Australia
    Centre for Vision and Eye Research, Queensland University of Technology, Brisbane, Queensland, Australia
  • Footnotes
    Commercial Relationships   Asik Pradhan None; Rohan Hughes None; Emily Pieterse None; David Atchison None; Stephen Vincent None; Scott Read None; Andrew Carkeet None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2022, Vol.63, 3066 – F0538. doi:
  • Views
  • Share
  • Tools
    • Alerts
      User Alerts
      You are adding an alert for:
      Assessment of crystalline lens shape during accommodation using IOLMaster 700 B-scan images
      You will receive an email whenever this article is corrected, updated, or cited in the literature. You can manage this and all other alerts in My Account
      The alert will be sent to:
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation
      Citation

      Asik Pradhan, Rohan Hughes, Emily Pieterse, David Andrew Atchison, Stephen Vincent, Scott Read, Andrew Carkeet; Assessment of crystalline lens shape during accommodation using IOLMaster 700 B-scan images. Invest. Ophthalmol. Vis. Sci. 2022;63(7):3066 – F0538.

      Download citation file:

      © ARVO (1962-2015); The Authors (2016-present)

      ×
    • Get Permissions
  • Supplements
Abstract

Purpose : The Zeiss IOLMaster 700® biometer offers image-based axial measurement of eye structures together with visualisation of the anatomical details in a longitudinal section. We aimed to analyse these B-scan images to determine crystalline lens shape changes induced by accommodation.

Methods : IOLMaster 700 B-scan images were acquired from 10 children (age: mean 11.1, SD 0.4 years) during 0D and 6D accommodation tasks. Scans were analysed using custom MATLAB software to determine the curvature measurements for anterior and posterior cornea and lens surfaces. The process involved segmenting the image to locate the corneal and lens surfaces (Figure 1), correcting for existing distortions in the image to reconstruct ray path distance maps, and using the maps with ray tracing to determine surface positions. Second order polynomials were fit to the surfaces to compute radii of curvature.

Results : The radius of curvature decreased significantly with accommodation for the anterior lens (t8 = 5.93, p = 0.0003) (0D accommodation: mean 13.26mm, SD 2.19mm; 6D accommodation: mean 8.87mm, SD 0.94mm) but not for posterior lens (p > 0.05) (0D accommodation: mean -5.62mm, SD 0.64mm; 6D accommodation: mean -5.11mm, SD 0.52mm), nor for anterior and posterior cornea. Results for all surfaces are shown in Figure 2 with data for one image (6D accommodation) discarded due to eye movement artefacts.

Conclusions : This is a novel analysis of the data contained in IOLMaster 700 images. The measured changes in both anterior and posterior lens surface curvature were comparable to previous studies that demonstrate its potential of measuring lens shape during accommodation. Because of the wide availability of IOLMaster 700, this may be a useful research tool for studying crystalline lens shape. Further research is required to establish repeatability and accuracy of the technique.

This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.

 

Figure 1: An exemplar of a B-scan image at the 180ο meridian obtained from IOLMaster 700 after segmentation using MATLAB. Fitted points are shown in green, red shows preliminary polynomial fits to surfaces, and blue shows discarded outliers.
View OriginalDownload Slide

Figure 1: An exemplar of a B-scan image at the 180ο meridian obtained from IOLMaster 700 after segmentation using MATLAB. Fitted points are shown in green, red shows preliminary polynomial fits to surfaces, and blue shows discarded outliers.

Figure 1: An exemplar of a B-scan image at the 180ο meridian obtained from IOLMaster 700 after segmentation using MATLAB. Fitted points are shown in green, red shows preliminary polynomial fits to surfaces, and blue shows discarded outliers.

Figure 1: An exemplar of a B-scan image at the 180ο meridian obtained from IOLMaster 700 after segmentation using MATLAB. Fitted points are shown in green, red shows preliminary polynomial fits to surfaces, and blue shows discarded outliers.
View OriginalDownload Slide
 
Figure 2: Box and whisker plots showing median, interquartile and range of the radius of curvature values for anterior and posterior corneal and lens surfaces at 0D and 6D accommodation demand
View OriginalDownload Slide

Figure 2: Box and whisker plots showing median, interquartile and range of the radius of curvature values for anterior and posterior corneal and lens surfaces at 0D and 6D accommodation demand

Figure 2: Box and whisker plots showing median, interquartile and range of the radius of curvature values for anterior and posterior corneal and lens surfaces at 0D and 6D accommodation demand

Figure 2: Box and whisker plots showing median, interquartile and range of the radius of curvature values for anterior and posterior corneal and lens surfaces at 0D and 6D accommodation demand
View OriginalDownload Slide

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Attribution-NonCommercial-NoDerivatives
Copyright © 2024 Association for Research in Vision and Ophthalmology.
×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×
This site uses cookies. By continuing to use our website, you are agreeing to our privacy policy.Accept