Abstract
Purpose :
The purpose of this study is to investigate the effect of blue-light-blocking intraocular lens (IOL) versus non-blue-light-blocking IOL placement during cataract surgery on sleep, mood, and Circadian rhythm in diabetic patients. Placement of a blue-light-blocking IOL may reduce exposure of the intrinsically photosensitive retinal ganglion cells to blue light, inhibiting the ability of these cells to synchronize the body’s Circadian rhythm, which may in turn affect sleep patterns and mood.
Methods :
We recruited 20 patients diagnosed with diabetes mellitus type 2 who were scheduled to undergo bilateral cataract surgery. Patients filled out the SCRAM (Sleep, Circadian Rhythms And Mood) Questionnaire before cataract surgery and again 1-3 months after cataract surgery. Changes in SCRAM Questionnaire answers before and after surgery were assessed to estimate the effect of IOL type.
Results :
In diabetic patients undergoing bilateral cataract surgery, across all types of IOL, SCRAM Questionnaire scores for Good Sleep increased by 3.39 (P = 0.45), Morningness increased by 0.08 (P = 0.98), and Depressed Mood decreased by 3.61 (P = 0.21). When patients receiving ultraviolet-light-blocking IOLs were compared to those receiving blue-light-blocking IOLs, their scores for Good Sleep increased by 7.99 less (P = 0.11), Morningness increased by 10.70 more (P = 0.17), and Depressed Mood decreased by 0.82 less (P = 0.72).
Conclusions :
These results suggest that cataract surgery may result in subjectively improved sleep quality and mood regardless of the type of IOL placed, although results were not statistically significant. No statistically significant improvement in sleep quality, Circadian rhythm, and mood was shown in patients receiving blue-light-blocking IOLs as compared to those receiving ultraviolet-light-blocking IOLs.
This abstract was presented at the 2022 ARVO Annual Meeting, held in Denver, CO, May 1-4, 2022, and virtually.