June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Effect of contact lens wear on tear film dynamics as measured by a novel Tear Film Imager (TFI)
Author Affiliations & Notes
  • Kelly Acuna
    University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Miami VA Medical Center, Miami, Florida, United States
  • Simran Mangwani
    University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Miami VA Medical Center, Miami, Florida, United States
  • Anat Galor
    University of Miami Health System Bascom Palmer Eye Institute, Miami, Florida, United States
    Miami VA Medical Center, Miami, Florida, United States
  • Footnotes
    Commercial Relationships   Kelly Acuna None; Simran Mangwani None; Anat Galor None
  • Footnotes
    Support  Supported by the Department of Veterans Affairs, Veterans Health Administration, Office of Research and Development, Clinical Sciences R&D (CSRD) I01 CX002015 (Dr. Galor), Biomedical Laboratory R&D (BLRD) Service I01 BX004893 (Dr. Galor), Rehabilitation R&D (RRD) I21 RX003883 (Dr. Galor), Department of Defense Gulf War Illness Research Program (GWIRP) W81XWH-20-1-0579 (Dr. Galor) and Vision Research Program (VRP) W81XWH-20-1-0820 (Dr. Galor), National Eye Institute U01 EY034686 (Dr. Galor), R01EY026174 (Dr. Galor), R61EY032468 (Dr. Galor), U01EY034686 (Dr. Galor), NIH Center Core Grant P30EY014801 (institutional) and Research to Prevent Blindness Unrestricted Grant GR004596-1 (institutional).
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 192. doi:
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    • Get Citation

      Kelly Acuna, Simran Mangwani, Anat Galor; Effect of contact lens wear on tear film dynamics as measured by a novel Tear Film Imager (TFI). Invest. Ophthalmol. Vis. Sci. 2023;64(8):192.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : The objective of this study was to compare tear film parameters with and without a contact lens (CL), utilizing a novel device, the Tear Film Imager (TFI), which can dynamically image the muco-aqueous and lipid layer of the tear film.

Methods : Two sequential images were obtained of the right eye of healthy individuals, first without a CL, and then with a CL. The nanometer resolution of the TFI enabled the creation of detailed maps across the corneal surface that provided information on tear film dynamics. The parameters measured included mucous-aqueous layer thickness (MALT), mucous-aqueous thickness change rate (MALTR), lipid layer thickness (LLT), lipid break-up time (LBUT), interblink interval (IBI), lipid map uniformity (LMU). The images captured natural blinking rates with a large field of view of 6.5 mm diameter.

Results : 13 subjects participated in the study with a mean age of 28.4±3.5 years and a female majority (69%). Of all parameters, MALT (3111.69±576.82 nm → 2357.38±621.73 nm, p=0.004) significantly changed with CL use (data displayed as pre vs post CL). No other significant differences were noted with respect to MALTR, LLT, LBUT, IBI, or LMU pre vs post CL.

Conclusions : Our study found that MALT decreased with placement of a CL, demonstrating the sensitivity of the TFI in detecting a change in tear film dynamics with an intervention, in this case CL placement.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

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