June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Endothelial cells migration after Descemet membrane fracture and detachment, secondary to forceps trauma during labor
Author Affiliations & Notes
  • Manuel Ramirez Fernandez
    Cornea, Asociacion para Evitar la Ceguera IAP Hospital Dr Luis Sanchez Bulnes, Mexico City, Mexico City, Mexico
  • Emmanuel Cabrera-Martinez
    Cornea, Asociacion para Evitar la Ceguera IAP Hospital Dr Luis Sanchez Bulnes, Mexico City, Mexico City, Mexico
  • Alejandro Toledo
    Cornea, Asociacion para Evitar la Ceguera IAP Hospital Dr Luis Sanchez Bulnes, Mexico City, Mexico City, Mexico
  • Itzel Aguilar-Valdez
    Cornea, Asociacion para Evitar la Ceguera IAP Hospital Dr Luis Sanchez Bulnes, Mexico City, Mexico City, Mexico
  • Emmanuel Romero
    Cornea, Asociacion para Evitar la Ceguera IAP Hospital Dr Luis Sanchez Bulnes, Mexico City, Mexico City, Mexico
  • Guillermo Dewit-Carter
    Cornea, Asociacion para Evitar la Ceguera IAP Hospital Dr Luis Sanchez Bulnes, Mexico City, Mexico City, Mexico
  • Footnotes
    Commercial Relationships   Manuel Ramirez Fernandez None; Emmanuel Cabrera-Martinez None; Alejandro Toledo None; Itzel Aguilar-Valdez None; Emmanuel Romero None; Guillermo Dewit-Carter None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 646. doi:
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      Manuel Ramirez Fernandez, Emmanuel Cabrera-Martinez, Alejandro Toledo, Itzel Aguilar-Valdez, Emmanuel Romero, Guillermo Dewit-Carter; Endothelial cells migration after Descemet membrane fracture and detachment, secondary to forceps trauma during labor. Invest. Ophthalmol. Vis. Sci. 2023;64(8):646.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate endothelial cells migration after Descemet membrane detachment by using AS-OCT and confocal microscopy

Methods : 3 eyes of three patients with Descemet membrane detachment diagnosis were studied by using SA-OCT OptoVue®( RTVue Fourier-Domain Optical Coherence Tomography System) to find this Descemet membrane detachment, central corneal confocal microscopy (Confoscan 4, Fortune Technologies, Italy) of the total corneal thickness were done, corneal endothelium was located at the confocal scan images in all cases, cell density and endothelial cells size were analyzed and measured by using the NAVIS software v. 3.5.0 in all cases (NIDEK Multi-Instrument Diagnostic System, Japan).

Results : AS-OCT showed total Descemet membrane detachment in all cases. Corneal endothelium were found by confocal microscopy in all cases behind the deepest corneal stroma image in all cases. Endothelial cell density was 1513.7 ± 208.6 mm2, Endothelial cells size was 35.3 ± 6.1 µm2.

Conclusions : Endothelial cells migration may happen after traumatic Descemet membrane fracture and detachment in new born patients after a forceps trauma in labor, endothelium can be found behind the corneal stroma.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

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