June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Diverse novel ganglion cell and amacrine cell types in the macaque and human retina revealed with large-scale recordings
Author Affiliations & Notes
  • E.J. Chichilnisky
    Neurosurgery & Ophthalmology, Stanford University, Stanford, California, United States
  • Footnotes
    Commercial Relationships   E.J. Chichilnisky None
  • Footnotes
    Support  NEI Grant EY029247, RPB Stein Innovation Award
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 510. doi:
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    • Get Citation

      E.J. Chichilnisky; Diverse novel ganglion cell and amacrine cell types in the macaque and human retina revealed with large-scale recordings. Invest. Ophthalmol. Vis. Sci. 2023;64(8):510.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Presentation Description : The visual processing properties of most of the 20+ retinal ganglion cell (RGC) types in the primate retina remain unknown. Using large-scale high-density multi-electrode recordings from macaque and human retinas, we reveal some of the basic spatial, temporal and chromatic response properties of 10+ novel RGC types that have been studied little or not at all, as well as a similar number of novel polyaxonal amacrine (PAC) cell types. Cell type identification is performed by quantitative clustering of stereotyped visual response properties, and confirmed by the mosaic organization of each identified type. The results reveal surprisingly diverse receptive field structure of novel RGC and PAC types, and high similarity between novel macaque and human cell types.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

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