Abstract
Purpose :
To evaluate eye growth of children wearing spectacle lenses with highly aspherical lenslets (HAL), slightly aspherical lenslets (SAL), and single-vision lenses (SVL) compared to eye growth patterns in non-myopic children in Wenzhou, China.
Methods :
The randomized trial had 170 myopic children in Wenzhou (8-13 years; SE of -0.75--4.75D) randomly assigned to wear 1 of the 3 spectacle lenses: HAL, SAL, or SVL for 2 years. Wearing time was assessed with questionnaires. Normal eye growth was examined using 700 schoolchildren (7-9 years), enrolled in the Wenzhou Medical University-Essilor Progression and Onset of Myopia (WEPrOM) cohort study, who were non-myopic (SE>-0.5D) for 2 annual visits between 2014 to 2018. A logistic function model was used. Slow, normal, and fast eye growth was defined as the range of values below 25th, within 25th and 75th, and above 75th percentiles, respectively.
Results :
The predicted upper limits of slow eye growth (25th percentile) among non-myopes aged 7-10 and 11-13 years was 0.20-0.13 and 0.08-0.01mm (after 2y period; 0.37-0.33 and 0.29-0.14mm), respectively, and upper limits of normal eye growth (75th percentile) was 0.32-0.31 and 0.28-0.10mm (after 2y period; 0.58-0.55 and 0.50-0.24mm), respectively.
A total of 157 (54 HAL, 53 SAL, and 50 SVL) children completed the 2-year trial, and 96 wore their lenses full-time every day ≥12 hours/day. The mean 1-year AL change for HAL, SAL, and SVL was 0.13, 0.24, and 0.37mm (0.08, 0.19, 0.37mm in full-time wearers [FTW]), respectively, and 2-year AL change was 0.34, 0.51, and 0.69mm (0.28, 0.46, 0.69mm in FTW), respectively.
After the first year in HAL, SAL, and SVL groups, slow eye growth was found in 43%, 13%, and 2% (53%, 20%, and 0% in FTW), normal eye growth in 30%, 49%, and 16% (34%, 60%, and 15% in FTW), and fast eye growth in 28%, 38%, and 82% (13%, 20%, and 85% in FTW), respectively (p<0.001). After the second year in HAL, SAL, and SVL groups, slow eye growth was found in 35%, 17%, and 2% (44%, 29%, and 3% in FTW), normal eye growth in 35%, 26%, and 12% (44%, 32%, and 9% in FTW), and fast eye growth in 30%, 57%, and 86% (12%, 39%, and 88% in FTW), respectively (p<0.001).
Conclusions :
The eye growth pattern in 9 of 10 wearing HAL full-time (compared to 1 of 10 wearing SVL full-time) was similar or slower than that of non-myopic children both after the first year and after a 2-year period.
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.