Abstract
Purpose :
Purpose: Bariatric surgery, as indicated for treatment of morbid obesity, has been commonly studied in association with short term effects on ocular pathology. However, effects of surgery on postoperative ocular disease incidence are largely unknown. This retrospective study utilizes a large US database to examine bariatric surgery and future risk of various ocular pathologies.
Methods :
Methods: The TriNetX U.S. Collaborative Network, a large national database, was queried for patients with an ICD 10 code for morbid obesity and a procedural code for bariatric surgery. Patients were matched across baseline demographics at the time of surgery and compared to those presenting with an ICD 10 code for morbid [RS1] [RM2] obesity with no records of a procedural code for bariatric surgery, identifying 47,040 patients in each cohort. New diagnoses or procedural codes found after the surgical index date for diabetic retinopathy, age-related macular degeneration, glaucoma, retinal vascular occlusion, cataract, low vision, and blindness along with pertinent treatment metrics were monitored.
Results :
Results: Bariatric surgery was found to be associated with significantly reduced future risk of diabetic retinopathy (RR: 0.448; 95% CI: 0.4-0.512), macular edema (RR: 0.404; 95% CI: 0.301-0.542), ocular hypertension (RR: 0.54; 95% CI: 0.425-0.687), glaucoma diagnoses (RR: 0.575; 95% CI: 0.521-0.636), use of ocular pressure lowering medications (RR: 0.802; 95% CI: 0.699-0.921), nonexudative age-related macular degeneration (RR: 0.646; 95% CI: 0.438-0.952), cataract surgery (RR: 0.82; 95% CI: 0.693-0.972), and low vision (RR: 0.541; 95% CI: 0.477-0.613) compared to patients who were not treated surgically.
Conclusions :
Conclusions: The present analysis comprising a large US cohort of patients suggests that bariatric surgery is associated with a decreased risk of future ocular morbidity.
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.