June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Longitudinal assessment of choroidal vascularity index in eyes with branch retinal vein occlusion-associated cystoid macular edema
Author Affiliations & Notes
  • Praruj Pant
    Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States
  • Anita Kundu
    Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States
  • Jay Rathinavelu
    Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States
  • Xin Wei
    Ophthalmology, Tan Tock Seng Hospital, Singapore, Singapore
  • Rupesh Vijay Agrawal
    Ophthalmology, Tan Tock Seng Hospital, Singapore, Singapore
  • Sandra Stinnett
    Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States
  • Jane S. Kim
    Ophthalmology, University of Michigan Michigan Medicine, Ann Arbor, Michigan, United States
  • Akshay Thomas
    Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States
  • Sharon Fekrat
    Ophthalmology, Duke University School of Medicine, Durham, North Carolina, United States
  • Footnotes
    Commercial Relationships   Praruj Pant None; Anita Kundu None; Jay Rathinavelu None; Xin Wei None; Rupesh Agrawal None; Sandra Stinnett None; Jane Kim None; Akshay Thomas None; Sharon Fekrat None
  • Footnotes
    Support  VitreoRetinal Surgery Foundation Research Award
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 1779. doi:
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      Praruj Pant, Anita Kundu, Jay Rathinavelu, Xin Wei, Rupesh Vijay Agrawal, Sandra Stinnett, Jane S. Kim, Akshay Thomas, Sharon Fekrat; Longitudinal assessment of choroidal vascularity index in eyes with branch retinal vein occlusion-associated cystoid macular edema. Invest. Ophthalmol. Vis. Sci. 2023;64(8):1779.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To assess choroidal vascularity index (CVI), subfoveal choroidal thickness (SFCT), and central subfield thickness (CST) in eyes with cystoid macular edema (CME) due to branch retinal vein occlusion (BRVO) compared to unaffected fellow eyes.

Methods : Retrospective longitudinal study of eyes with treatment-naïve BRVO with CME. Enhanced depth imaging optical coherence tomography (EDI-OCT) images were collected at baseline and 12-month follow-up visit. CVI, SFCT and CST were measured. Demographics, treatment patterns and visual acuity (VA) were abstracted. Median CVI, SFCT, CST, and VA were compared between two cohorts: 1) BRVO eyes and 2) unaffected fellow eyes. Longitudinal relationships between these variables were analyzed.

Results : Baseline CVI was lower in BRVO vs. fellow eyes (64.7% vs 66.4%, p=0.003). At 12-months, there was no difference in CVI between BRVO and fellow eyes (65.7% vs 65.8%, p=0.536). In BRVO eyes, there was a strong correlation between reduced CST and improved VA over the study period (r = 0.671, p<0.001).

Conclusions : There are differences in choroidal vascularity in treatment-naïve BRVO eyes with CME at baseline compared to fellow eyes, but these differences resolve over time. Anatomic changes in CST in BRVO eyes with CME may be correlated with long-term visual outcomes.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

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