June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Effect of Contact Lenses on Corneal Biomechanical Properties of Allergic Conjunctivitis Patients.
Author Affiliations & Notes
  • Masahiro Yamaguchi
    Ophthalmology, Juntendo Daigaku, Bunkyo-ku, Tokyo, Japan
  • Sakyo Kanehara
    Ophthalmology, Inoue Ganka Byoin, Tokyo, Chiyoda-ku, Japan
    Ophthalmology, Juntendo Daigaku, Bunkyo-ku, Tokyo, Japan
  • Noboyuki Ebihara
    ophthalmology, Juntendo Daigaku Igakubu Fuzoku Urayasu Byoin, Urayasu, Chiba, Japan
    Ophthalmology, Juntendo Daigaku, Bunkyo-ku, Tokyo, Japan
  • Yoshimune Hiratsuka
    Ophthalmology, Juntendo Daigaku, Bunkyo-ku, Tokyo, Japan
  • Footnotes
    Commercial Relationships   Masahiro Yamaguchi None; Sakyo Kanehara None; Noboyuki Ebihara None; Yoshimune Hiratsuka None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 1690. doi:
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      Masahiro Yamaguchi, Sakyo Kanehara, Noboyuki Ebihara, Yoshimune Hiratsuka; Effect of Contact Lenses on Corneal Biomechanical Properties of Allergic Conjunctivitis Patients.. Invest. Ophthalmol. Vis. Sci. 2023;64(8):1690.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : Allergic conjunctivitis (AC) has been reported to decrease corneal biomechanical properties. (Wang et al. 2021) We also found in a multivariate analysis adjusting for age, IOP, and corneal thickness that AC decreases biomechanical properties in normal eyes. (manuscript in preparation) In this study, we investigated whether soft contact lens (SCL) wear affects corneal biomechanical properties in patients with AC.

Methods : The biomechanical properties of the cornea were analyzed in two groups: SCL-wearing group (CL group, 20 eyes in 12 cases) and SCL-unwearing group (NCL group, 12 eyes in 6 cases). The biomechanical parameters (TBI, CBI, SPA1, peak distance, and radius) were analyzed using a regression model since they were affected by age, corneal thickness, and intraocular pressure. SSI was an independent factor from corneal thickness and IOP and was analyzed in t-test.

Results : Age, IOP, corneal thickness, and spherical refraction were 27.3 vs. 29.3 years, 16.0 vs. 16.4 mmHg, 508.5 vs. 535.9 μm, and -4.1 vs. -2.0 D in the CL and NCL groups, respectively ( p=0.43, 0.14, 0.002, 0.07 ). Eight patients used daily disposable lenses and four patients used two weeks disposable lenses. Radius, TBI, CBI, SPA1, or Peak distance were not affected by SCL wear (p=0.0.99, 0.08, 0.22, 0.08). The independent factor SSI was decreased by SCL wear in CLG (p=0.02).

Conclusions : It may suggest that corneal biomechanical properties of AC patients may be decreased by SCL wear.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

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