Abstract
Purpose :
To report outcomes of simultaneous corneal crosslinking (CXL) and Transepithelial Topography-guided Photorefractive Keratectomy (TE-TGPRK) in eyes with keratoconus.
Methods :
TE-TGPRK with simultaneous CXL was performed in 21 eyes of 18 patients. All patients underwent TE-TGPRK with Contoura Vision software on the Wavelight Eye Q excimer laser (Alcon, Fort Worth, TX). All patients were treated with simultaneous CXL (5.4 J/cm2). Postoperative uncorrected and best corrected visual acuity (UCVA, BCVA), manifest refraction spherical equivalent (MRSE), maximum (Kmax) and average (Kavg) keratometry, thinnest pachymetry (Pthin), and inferior superior (IS) value were measured at 1 year follow-up.
Results :
At 1 year, UCVA improved by -0.27±0.44 logMAR lines (LL) (p=.01) and BCVA improved by -0.12±0.23LL (p=.03). MRSE changed by 0.17±3.43D (p=.83). Kmax flattened from 58.0±6.5D to 52.6±5.6D (p<.001) and Kavg flattened from 48.9±3.8D to 46.6±3.4D (p<.001). IS improved from 11.6±3.9D to 8.5±4.5D (p<.001) and Pthin decreased by -49.1±52.1µm (p<.001).
Conclusions :
Simultaneous TE-TGPRK/CXL significantly improved UCVA and BCVA, and corneal topography (Kmax, Kavg, and IS difference). TE-TGPRK/CXL appears to be a promising treatment for patients with keratoconus.
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.