Abstract
Purpose :
Visual acuity is often suboptimal despite successful repair of rhegmatogenous retinal detachment (RRD). We evaluated retinal microvasculature and photoreceptor layer thickness with novel SS-OCTA, after successful surgery for macula off RRD to explain this discrepancy despite restoration of normal anatomy
To correlate swept source optical coherence tomography angiography (SS-OCTA) measured macular perfusion changes with best corrected visual acuity (BCVA) in macula off retinal detachments (MORRD) after successful surgery
Methods :
In this large study, SS-OCTA was performed (8X8mm) to evaluate the macular perfusion changes in MORRD (N=142), 90 days after successful surgery. Superficial capillary plexus (SCPFD), deep capillary plexus (DCPFD), foveal avascular zone (FAZ) and thickness of various layers were measured. Fellow eyes served as control
Results :
Superficial capillary perfusion flow density and deep capillary perfusion flow density were 32.18% ± 0.99% and 31.06% ± 2.22% vs 36.11%±1.29% and 37.52±1.24% (P<0.001). Foveal avascular zone was larger 0.702 vs 0.543 (P<0.001). Best corrected visual acuity strongly correlated with deep capillary perfusion density (r=0.712) and photoreceptor layer thickness (PCLT) (r=0.541) and size of foveal avascular zone (r=0.482)
Conclusions :
In this large study (N=142), visual acuity strongly correlated (r=0.72) with noninvasive swept source angiography (Plexilite, Zeiss) measured (8X8mm) deep capillary retinal flow index in fovea and photoreceptor layer thickness after successful repair of macula off retinal detachment (3 months after surgery) and explained suboptimal vision despite normal anatomy in selected subjects
SS-OCTA measured DCPFD in fovea and PCLT strongly correlate with BCVA in MORRD after surgery and provide for suboptimal visual gain despite normal anatomy in select subjects
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.