June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Chromatic aberration in intraocular lens technologies to extend depth of focus
Author Affiliations & Notes
  • Antonio Del Aguila-Carrasco
    R&D, Johnson & Johnson Surgical Vision, Groningen, Netherlands
  • Henk A Weeber
    R&D, Johnson & Johnson Surgical Vision, Groningen, Netherlands
  • Aixa Alarcon
    R&D, Johnson & Johnson Surgical Vision, Groningen, Netherlands
  • Patricia Piers
    R&D, Johnson & Johnson Surgical Vision, Groningen, Netherlands
  • Footnotes
    Commercial Relationships   Antonio Del Aguila-Carrasco Johnson & Johnson, Code E (Employment); Henk Weeber Johnson & Johnson, Code E (Employment); Aixa Alarcon Johnson & Johnson, Code E (Employment); Patricia Piers Johnson & Johnson, Code E (Employment)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 2520. doi:
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      Antonio Del Aguila-Carrasco, Henk A Weeber, Aixa Alarcon, Patricia Piers; Chromatic aberration in intraocular lens technologies to extend depth of focus. Invest. Ophthalmol. Vis. Sci. 2023;64(8):2520.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : The longitudinal chromatic aberration (LCA) of intraocular lenses (IOLs) depends upon the IOL design and dispersion of the material, and it shows as a difference in focus of light with different wavelengths.
The purpose of this work was to determine the LCA of different extended depth of focus (EDF) IOLs for different pupil sizes, both for distance and intermediate vision.

Methods : Through-focus modulation transfer function (MTF) at 50 c/mm of different IOL models in a model eye with a cornea that reproduces the average spherical aberration (SA) and LCA of the human cornea were obtained for five different wavelengths (450, 500, 550, 600 and 650 nm) and for pupil sizes ranging from 1 to 5 mm in 1 mm steps. The lenses measured were an aspheric monofocal (M), a monofocal that slightly extends depth of focus (sEDF) and four aspheric EDF with different technologies: diffractive (EDF1), wavefront shaping (EDF2), and refractive (EDF3 and a new design, EDF4). EDF1 and EDF4 fully compensate for average corneal SA, EDF3 induces zero SA and EDF2 partially compensates for average corneal SA. LCA was calculated as the difference in defocus between the peaks at 650 nm and at 450 nm on the through-focus MTF for both distance and intermediate peaks.

Results : LCA obtained for distance vision with a 3 mm diameter was 1.36 D, 1.34 D, 0.84 D, 1.79 D, 1.61 D and 1.44 D for M, sEDF, EDF1, EDF2, EDF3 and EDF4, respectively. For intermediate vision and a 3-mm pupil size, LCA was 1.33 D, 0.73 D, 1.86 D, 1.70 D and 1.38 D for EM, EDF1, EDF2, EDF3 and EDF4, respectively. For distance, the maximum through pupil change in LCA was comparable for all lens models (about 0.1 D), except for the diffractive EDF (EDF1), that showed a change in LCA of 0.79 D. Regarding intermediate vision, there was less than 0.1D difference for different pupils for all the lenses, except for the diffractive and wavefront shaping EDF IOLs, that showed a change of 0.89 D and 1.4 D, respectively.

Conclusions : For refractive IOLs, LCA remains virtually constant for all pupil sizes, whereas for IOLs with diffractive and wavefront shaping technologies, LCA experiences abrupt changes with pupil size. Diffractive technology partly compensates for refractive LCA, leading to smaller LCA values. The new EDF IOL (EDF4) demonstrated a refractive behavior, as its LCA was practically constant for all pupil sizes.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

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