June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Evaluation of Enhanced Monofocal Plus IOLs with Extended Depth of Focus
Author Affiliations & Notes
  • George M Lau
    Medical Affairs, Bausch and Lomb, Bridgewater, New Jersey, United States
  • Lester Hosten
    Medical Affairs, Bausch and Lomb, Bridgewater, New Jersey, United States
  • Valeri Kolesnitchenko
    Medical Affairs, Bausch and Lomb, Bridgewater, New Jersey, United States
  • Footnotes
    Commercial Relationships   George Lau Bausch and Lomb, Code E (Employment); Lester Hosten Bausch and Lomb, Code E (Employment); Valeri Kolesnitchenko Bausch and Lomb, Code E (Employment)
  • Footnotes
    Support  none
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 2518. doi:
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    • Get Citation

      George M Lau, Lester Hosten, Valeri Kolesnitchenko; Evaluation of Enhanced Monofocal Plus IOLs with Extended Depth of Focus. Invest. Ophthalmol. Vis. Sci. 2023;64(8):2518.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : New monofocal plus lens designs extend depth of focus into intermediate distances. The increase in the range of focus comes at the cost of reducing distance image contrast. Prior experience with multifocal designs has shown that reduction in image contrast is tolerated without any compromise until certain MTF thresholds with 50 lp/mm (equivalent to 20/40 vision) as a proxy for clinical performance. A new monofocal plus IOL (enVista Aspire) from Bausch &Lomb has been developed to provide a continuous depth of focus from distance to intermediate. This laboratory study will measure and compare MTF values and USAF images between the original enVista monofocal (MX60E), the new enVista Aspire (EA), and a comparator Tecnis Eyhance (DIB00) from Johnson & Johnson.

Methods : MTF values were measured at 50 lp/mm with an ISO 1 model cornea with zero spherical aberration on the Trioptics optical bench. USAF resolution targets were also imaged at different defocus locations in steps of 0.25D. IOLs within a power range of 18.0D to 22.0D were used.

Results : The new monofocal plus design (EA) gave a continuous range of vision from distance to at least 1.0D with higher contrast when compared to DIB00. MX60E had the highest distance MTF and DIB00 had the lowest. EA showed higher intermediate MTF between 0.5D to 1.0D when compared to MX60E and DIB00.

Conclusions : The Eyhance lens had the lowest MTF at distance and ≤0.20 MTF units between 0.5D and 1.25D which could compromise optical performance. In comparison, Aspire lens had higher MTF at distance with ≥0.2 MTF units between 0.5D to 1.0D, providing a continuous range of focus with uncompromised visual quality at intermediate distances.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

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