June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Remote assessment of patients with red eyes utilzing anterior segment optical coherence tomography – a pilot study.
Author Affiliations & Notes
  • Christopher Erwin
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • Sumit Sharma
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • Megan Ann McDonald
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • SANDEEP SINGH
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • Naveen Karthik
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • Kimberly Baynes
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • Danielle X Burton
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • Kaylnn Cuson
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • Sunil K Srivastava
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • Footnotes
    Commercial Relationships   Christopher Erwin None; Sumit Sharma Abbvie, Allergan, Eyepoint, Clearside, Bausch and Lomb, Genentech, Regeneron, Regenxbio, Apellis, Code C (Consultant/Contractor), Genentech, Roche, IONIS, Santen, Gilead, Code R (Recipient); Megan McDonald None; SANDEEP SINGH None; Naveen Karthik None; Kimberly Baynes None; Danielle Burton None; Kaylnn Cuson None; Sunil Srivastava Novartis, Eyepoint, Bausch, Eyevensys, jCyte, Abbvie, Zeiss, Code C (Consultant/Contractor), Eyepoint, Regeneron, Santen, Allergan, Eyevensys, Code F (Financial Support)
  • Footnotes
    Support  P30EY025585, Research to Prevent Blindness (RPB) Challenge Grant, Cleveland Eye Bank Foundation Grant
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 3408. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Christopher Erwin, Sumit Sharma, Megan Ann McDonald, SANDEEP SINGH, Naveen Karthik, Kimberly Baynes, Danielle X Burton, Kaylnn Cuson, Sunil K Srivastava; Remote assessment of patients with red eyes utilzing anterior segment optical coherence tomography – a pilot study.. Invest. Ophthalmol. Vis. Sci. 2023;64(8):3408.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : Anterior segment spectral domain optical coherence tomography has been used to assess several causes of a red eye including anterior chamber inflammation, corneal ulcers and scleritis. In this pilot project, we sought to assess the correlation between clinician assessment of patients presenting with a red eye and remote grading of AS-OCT imaging.

Methods : In this IRB approved study, red eye patients presenting to an optometry office had slit lamp examination performed. On the same day, AS-OCT images were obtained (Optovue Avanti) including the anterior chamber (AC), cornea and sclera. Images were then read by a student reader and an expert ophthalmologist reader using customized software which identifies AC cell and provides an automated cellular density metric. Qualitative assessment of the cornea and scleral images were performed. A diagnosis was then determined by each reader. These results were compared to the clinician based examination.

Results : A total of 42 eyes of 21 patients (15 men) were evaluated. The mean age was 49. 20 eyes were normal, 13 eyes had uveitis, 3 eyes had scleritis and 4 eyes had keratitis. Correlation between clinician and expert grader was high – 39 out of 42 eyes were graded correctly. A novice student grader correctly graded 33 of 42 eyes. All eyes with uveitis were correctly diagnosed both graders. The mean AC cellular density was 113 cells/mm3 in uveitis eyes. Of the 3 eyes that had a different diagnosis by the expert grader, 2 eyes had scleral thickening noted by the reader but not the clinician and 1 eye had a diagnosis of keratitis in an area not imaged by OCT. Of the 9 eyes misdiagnosed by the novice reader, the most common diagnosis missed were keratitis and normal eyes interpreted to have scleral thickening by the reader.

Conclusions : In this pilot study, remote assessment of anterior segment optical coherence tomography of red eye patients correlated very highly with clinician assessment. A larger study is warranted to determine if remote automated OCT assessment of red eyes could accurately diagnose symptomatic red eye patients. Preliminary data points to the need for more complete corneal imaging and specific training on interpreting scleral images as areas for improvement.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×