June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Repeatability of full-field electroretinography parameters in patients with unilateral retinal vasculitis
Author Affiliations & Notes
  • Vahid Bazojoo
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • SungWho Park
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Hassan Khojasteh
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Amir Akhavanrezayat
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Irmak Karaca
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Chris Or
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Negin Yavari
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Azadeh Mobasserian
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Ngoc Than
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Prapatsorn Ongpalakorn
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Hashem Ghoraba
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Albert Bromeo
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • YongUn Shin
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Xun Lyu
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Lorrella Cabael
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Quan Dong Nguyen
    Ophthalmology, Stanford Medicine, Stanford, California, United States
  • Footnotes
    Commercial Relationships   Vahid Bazojoo None; SungWho Park None; Hassan Khojasteh None; Amir Akhavanrezayat None; Irmak Karaca None; Chris Or None; Negin Yavari None; Azadeh Mobasserian None; Ngoc Than None; Prapatsorn Ongpalakorn None; Hashem Ghoraba None; Albert Bromeo None; YongUn Shin None; Xun Lyu None; Lorrella Cabael None; Quan Nguyen Belite Bio, Code F (Financial Support), Genentech, Code F (Financial Support), Kriya, Code F (Financial Support), Regeneron, Code F (Financial Support), Rezolute, Code F (Financial Support)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 3333. doi:
  • Views
  • Share
  • Tools
    • Alerts
      ×
      This feature is available to authenticated users only.
      Sign In or Create an Account ×
    • Get Citation

      Vahid Bazojoo, SungWho Park, Hassan Khojasteh, Amir Akhavanrezayat, Irmak Karaca, Chris Or, Negin Yavari, Azadeh Mobasserian, Ngoc Than, Prapatsorn Ongpalakorn, Hashem Ghoraba, Albert Bromeo, YongUn Shin, Xun Lyu, Lorrella Cabael, Quan Dong Nguyen; Repeatability of full-field electroretinography parameters in patients with unilateral retinal vasculitis. Invest. Ophthalmol. Vis. Sci. 2023;64(8):3333.

      Download citation file:


      © ARVO (1962-2015); The Authors (2016-present)

      ×
  • Supplements
Abstract

Purpose : The impact of presence of ocular inflammation on the repeatability of full-field electroretinography (ffERG) parameters are unclear. Repeatability of ffERG testing is of significance in the functional assessment of patients with retinal vasculitis (RV). The present cross-sectional study investigated intra-visit repeatability of ffERG parameters in patients with RV.

Methods : Medical records of patients who were diagnosed with unilateral RV and underwent ffERG from December 2018 to August 2022 were included. RV was diagnosed based on wide-angle fluorescein angiography (WAFA). Angiography Scoring for Uveitis Working Group (ASUWOG) score was utilized to grade the severity of RV in affected eyes. ffERG testing using the Diagnosys® device was performed two times consecutively by the same operator, using the same settings in each session according to the International Society for Clinical Electrophysiology of Vision (ISCEV) recommendation. Repeatability of 14 parameters included amplitude and implicit parameters of dark adapted (DA) 0.01, 3, 3 oscillatory potentials (OP), DA 10, light adapted (LA) 3, LA 3 OP and LA 30 Hz flicker was assessed by using the intra-class correlation coefficient (ICC). ICC values of the amplitude and the implicit time were compared between eyes with RV and healthy fellow eyes. ICC values of the amplitude were also compared with those of the implicit time.

Results : A total of 17 patients (6 males and 11 females) with a median age of 33 (18-55) were included. ASUWOG score was 11.7±5.8 in the affected eyes. There was no statistically significant difference between the eyes with RV and healthy fellow eyes in terms of visual acuity (LogMAR 0.07±0.11 vs. 0.04±0.09, p=0.186) and central subfield macular thickness (297.5±102.0 μm vs. 265.5±42.1 μm, p=0.084). Mean ICC of seven amplitude parameters was 0.948±0.028 in eyes with RV and 0.948 ±0.027 in the healthy fellow eyes (p=0.495). Similarly, mean ICC of seven implicit time parameters was 0.850 ±0.084 in eyes with RV and 0.815 ±0.129 in healthy fellow eyes (p=0.224). Mean ICC of seven amplitude parameters in both eyes was 0.948±0.026, which was higher than mean ICC of 0.833±0.103 in seven implicit time parameters (p<0.001).

Conclusions : Repeatability of ffERG parameters is maintained similarly in eyes with RV and healthy fellow eyes. The amplitude parameters have higher repeatability than the implicit time parameters.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

×
×

This PDF is available to Subscribers Only

Sign in or purchase a subscription to access this content. ×

You must be signed into an individual account to use this feature.

×