Abstract
Purpose :
Established in 2014, The American Academy of Ophthalmology’s IRIS® Registry (Intelligent Research In Sight) has the ability to reveal information about disease prevalence, epidemiology, and pathology, as well as understand procedural and medical treatments in the real-world setting. We performed a trends analysis of IRIS Registry publications.
Methods :
Data was collected for the IRIS Registry publications as of December 2022 listed on the American Academy of Ophthalmology’s website. Article year of publication, journal, type of literature, subspecialty topic, specific disease or procedure of interest, and source of funding were recorded. Percentages were rounded to the nearest whole number.
Results :
54 articles were included with the rate of publication increasing over time. In 2015 and 2016, only two IRIS Registry publications were recorded while in 2021 and 2022, 36 publications were recorded. 43% articles were published in Ophthalmology, 17% in American Journal of Ophthalmology, 7% in Ophthalmology Science. JAMA Ophthalmology, Ophthalmology Retina and Ophthalmology Glaucoma each published 6% of IRIS registry articles. The most prevalent subspeciality topics were retina (35%), glaucoma (17%), and cataracts (15%). 48% of the publications focused on specific procedural treatments, 17% focused on disease epidemiology, and 13% focused on specific medical treatments. The majority of publications were original articles (82%) while the remainder were reports (7%), reviews (7%), editorials (2%), and research correspondences (2%). 6% of publications reported funding solely from the IRIS Grant, 41% of publications obtained funding solely from other means and 19% of publications obtained funding from a combination of the IRIS Grant and other means. The most commonly studied diseases among IRIS Registry publications were glaucoma (19%), age-related macular degeneration (9%) , and cataracts (7%). The two most frequently studied treatments were anti-vascular endothelial growth factors (11%) and cataract surgery (11%).
Conclusions :
These findings suggest that the IRIS Registry has already provided insight into a wide variety of clinical ophthalmology studies regarding specific disease and treatment analyses, epidemiological statistics, and more. This tool should continue to be utilized to further progression of the field.
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.