Abstract
Presentation Description :
Sickle cell disease (SCD) affects 100,000 Americans and millions worldwide. SCD is a blood disorder characterized by abnormal organ perfusion due to red blood cell damage, hemolysis and vaso-occlusion. The transparent media of the eye offers a unique opportunity to directly visualize abnormal perfusion of the retinal microvasculature, as an indirect representation of the microvascular status of other organ systems. Optical coherence tomography angiography (OCTA) and adaptive optics scanning light ophthalmoscopy (AOSLO) are two emerging technologies for in-vivo and non-invasive imaging of the human retinal vasculature. In this talk, we will present quantitative and qualitative measurements using these approaches for imaging abnormal perfusion in patients with SCD.
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.