Investigative Ophthalmology & Visual Science Cover Image for Volume 64, Issue 8
June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Intravitreal Ozurdex in children with paeditatric uveitis requiring cataract surgery
Author Affiliations & Notes
  • Senthil Selvam
    Medical Retina, Moorfields Eye Hospital NHS Foundation Trust, London, London, United Kingdom
  • Bejal Shah
    Medical Retina, Moorfields Eye Hospital NHS Foundation Trust, London, London, United Kingdom
  • Harry Petrushkin
    Medical Retina, Moorfields Eye Hospital NHS Foundation Trust, London, London, United Kingdom
  • Footnotes
    Commercial Relationships   Senthil Selvam None; Bejal Shah None; Harry Petrushkin None
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 3566. doi:
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      Senthil Selvam, Bejal Shah, Harry Petrushkin; Intravitreal Ozurdex in children with paeditatric uveitis requiring cataract surgery. Invest. Ophthalmol. Vis. Sci. 2023;64(8):3566.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate the safety and outcomes for children with paediatric uveitis who are pre-treated with intravitreal Ozurdex prior to undergoing cataract surgery.

Methods : A retrospective analysis of the electronic medical records was perfromed to identify all patients under 16 with uveitis that had undergone Ozurdex injection prior to cataract surgery. Data items in the audit dataset included: Demographics (hospital number, DOB, Date of surgery, age at time of surgery, gender), Time between Ozurdex injection and surgery, IOP data(pre-existing OHT requiring topical IOP lowering treatment, IOP pre-injection, IOP pre-op, IOP at first post-op visit, IOP at 3 months post-op), Visual Acuity date ( VA pre-op and VA 3 months post-op).

Results : 6 eyes of 5 patients were identified between 2012 - 2021, with an average age at time of surgery of 11.3 years (SD 3.9 years).
4 out of the 6 patients had improved visual acuity at 3 months post-op. The other two patients had improved vision by 6 months. There were no cases of permanent vision loss and no patients reuired lesn explantation.
2 patients had ocular hypertension after injection or surgery, with only 1 requiring surgical trabeculectomy.

Conclusions : This small case series shows that Ozurdex can be used safely in paediatric patients prior to cataract surgery with appropriate monitoring of patients pre and post intervention

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

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