June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Longitudinal Goniotomy Outcomes in Pseudoexfoliative Glaucoma
Author Affiliations & Notes
  • Kevin Zhang
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • Shirley Wu
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • Madhukar Kumar
    Case Western Reserve University School of Medicine, Cleveland, Ohio, United States
  • Andy Kuo
    Case Western Reserve University School of Medicine, Cleveland, Ohio, United States
  • Thanvi Vatti
    Case Western Reserve University School of Medicine, Cleveland, Ohio, United States
  • Ang Li
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, United States
  • Footnotes
    Commercial Relationships   Kevin Zhang None; Shirley Wu None; Madhukar Kumar None; Andy Kuo None; Thanvi Vatti None; Ang Li None
  • Footnotes
    Support  This study was supported in part by the NIH-NEI P30 Core Grant (IP30EY025585), Unrestricted Grants from The Research to Prevent Blindness, Inc., and Cleveland Eye Bank Foundation awarded to the Cole Eye Institute
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 4266. doi:
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    • Get Citation

      Kevin Zhang, Shirley Wu, Madhukar Kumar, Andy Kuo, Thanvi Vatti, Ang Li; Longitudinal Goniotomy Outcomes in Pseudoexfoliative Glaucoma. Invest. Ophthalmol. Vis. Sci. 2023;64(8):4266.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : The effect of goniotomy specifically for pseudoexfoliative glaucoma (PXG) has not been studied extensively. We describe the effects of goniotomy for PXG over a follow up time of 4 years.

Methods : This is an IRB-approved retrospective chart review for a multi-surgeon, large academic center using the CPT code 65820 for goniotomy from January 2012 to May 2022. Charts were individually reviewed and only Kahook Dual Blade and TrabEx surgeries for PXG patients were included in the analysis. Intraocular pressure (IOP) measurements and reduction of medication burden were recorded at various time points from 1 month to 4 years after surgery. Patients with inadequate follow up were excluded. Data points were collected up until a subsequent glaucoma surgery was performed, if applicable.

Results : In total, 32 eyes were included in this analysis. Baseline IOP prior to surgery was 18.9 +/- 7.1 mmHg. Mean reduction of IOP at 6 months, 1 year, 2 years, 3 years, and 4 years after surgery respectively were 4.9 +/- 6.5 mmHg (p=0.006), 4.9 +/- 6.7 mmHg (p=0.007), 5.4 +/- 8.1 mmHg (p=0.033), 4.8 +/- 9.4 mmHg (p=0.097), 5.0 +/- 6.6 mmHg (p=0.115). At the preoperative period, mean number of glaucoma medications was 2.2 +/- 1.3 drops with reduction to 1.4 +/- 1.5 drops (p=0.069) at the time of the latest follow up.

Conclusions : Goniotomy is an effective surgical option for PXG with reduction in IOP seen in the first two years. There was no statistically significant difference in medication burden after goniotomy for PXG.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

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