Abstract
Purpose :
Diffusion Optics Technology (DOT) spectacle lenses from SightGlass Vision have demonstrated the ability to control the progression of myopia in children. These lenses contain a clear central area encircled by a treatment zone with light scattering micro-dots which are reported to reduce peripheral contrast. The primary objective of this study was to compare threshold contrast sensitivity (CS) between DOT myopia control and standard single vision (SV) spectacle lenses (optimal correction and +0.50 D induced blur) in the lens periphery and centrally.
Methods :
Ten healthy subjects (5 male) 20-31 years of age (mean±SD, 23.9±3.5) were enrolled and optimally corrected to view a distance target at 4m through spectacle lenses with their right eye. FrACT contrast sensitivity (CS) threshold was measured at 3, 6, 12 and 18 cycles per degree (cpd) while subjects viewed through the central clear area and a peripheral portion with the pupil entirely outside central area of DOT lenses and SV lenses, as well as a SV lens with +0.50 D of blur. Equivalence testing was performed using an equivalence criterion based on published normative data.
Results :
Mean logCS values for both SV and DOT lenses when viewing through the central clear optics were, as expected, generally higher for low spatial frequencies (SF) (3cpd: SV = 2.03±0.22; DOT = 2.02±0.19), and lower at the higher SF (18cpd: SV = 1.53±0.32; DOT = 1.52±0.28). LogCS through the peripheral section with DOT lenses was slightly lower but statistically equivalent (p>0.05) and not clinically different (<0.2 log unit) compared to SV (3cpd: SV = 2.05±0.18 and DOT = 1.90±0.18; 18cpd: SV = 1.59±0.17 and DOT = 1.42±0.32). LogCS was statistically equivalent through the central and peripheral lens sections of DOT and SV lenses. LogCS with +0.50 D of induced blur was statistically equivalent and not clinically different than that of the SV or DOT lenses in either the central or peripheral sections (central: 3cpd: 1.93±0.17, 18cpd: 1.48±0.29; peripheral: 3cpd: 1.96±0.19, 18cpd: 1.52±0.28).
Conclusions :
DOT lenses provided CS statistically and clinically equivalent to standard SV and +0.50D blur through the central clear aperture and treatment zone. Thus, wearers of DOT lenses are not expected to notice substantial decreases in contrast when viewing through the clear lens center or when their eyes are turned to look through the treatment zone.
This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.