June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Contrast Sensitivity After a Lenticule Removal Procedure with a New Femtosecond Laser System
Author Affiliations & Notes
  • Michal Laron
    Johnson and Johnson Vision, Jacksonville, Florida, United States
  • Mahipal Sachdev
    Centre for Sight, New Delhi, Delhi, India
  • Rohit Shetty
    Narayana Nethralaya, Bangalore, Karnataka, India
  • Brian Schwam
    Johnson and Johnson Vision, Jacksonville, Florida, United States
  • Ritika Sachdev
    Centre for Sight, New Delhi, Delhi, India
  • Pooja Khamar
    Narayana Nethralaya, Bangalore, Karnataka, India
  • Raghav Malik
    Centre for Sight, New Delhi, Delhi, India
  • Andrew Voorhees
    Johnson and Johnson Vision, Jacksonville, Florida, United States
  • Hong Fu
    Johnson and Johnson Vision, Jacksonville, Florida, United States
  • Ying Wang
    Johnson and Johnson Vision, Jacksonville, Florida, United States
  • Priya Janakiraman
    Johnson and Johnson Vision, Jacksonville, Florida, United States
  • Alejandra Gonzalez Calle
    Johnson and Johnson Vision, Jacksonville, Florida, United States
  • Luis Vargas
    Johnson and Johnson Vision, Jacksonville, Florida, United States
  • Footnotes
    Commercial Relationships   Michal Laron Johnson & Johnson Vision, Code E (Employment); Mahipal Sachdev Centre for Sight, Code C (Consultant/Contractor); Rohit Shetty narayana nethralaya , Code C (Consultant/Contractor); Brian Schwam Johnson & Johnson Vision, Code E (Employment); Ritika Sachdev Centre for Sight, Code C (Consultant/Contractor); Pooja Khamar Narayana Nethralaya, Code C (Consultant/Contractor); Raghav Malik Centre for Sight, Code C (Consultant/Contractor); Andrew Voorhees Johnson & Johnson Vision, Code E (Employment); Hong Fu Johnson & Johnson Vision, Code E (Employment); Ying Wang Johnson & Johnson Vision, Code E (Employment); Priya Janakiraman Johnson & Johnson Vision, Code E (Employment); Alejandra Gonzalez Calle Johnson & Johnson Vision, Code E (Employment); Luis Vargas Johnson & Johnson Vision, Code E (Employment)
  • Footnotes
    Support  None
Investigative Ophthalmology & Visual Science June 2023, Vol.64, 4816. doi:
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      Michal Laron, Mahipal Sachdev, Rohit Shetty, Brian Schwam, Ritika Sachdev, Pooja Khamar, Raghav Malik, Andrew Voorhees, Hong Fu, Ying Wang, Priya Janakiraman, Alejandra Gonzalez Calle, Luis Vargas; Contrast Sensitivity After a Lenticule Removal Procedure with a New Femtosecond Laser System. Invest. Ophthalmol. Vis. Sci. 2023;64(8):4816.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Purpose : To evaluate the change in contrast sensitivity after lenticule removal procedure with a new femtosecond laser (nFS) system.

Methods : A prospective, multicenter, open-label, bilateral lenticule removal clinical study for myopic correction was performed. Ninety-nine subjects were treated with mean age of 27.0±6.4 SD. For each subject, a lenticule was created in both eyes using an nFS laser and was then removed for vision correction. Mean pre-op MRSE was -4.53D and ranged from -1.50D to -9.38D. Contrast sensitivity (CS) data was measured pre-op, and then starting at the 3-mo post-op visit. CS was measured in mesopic conditions with and without glare at 1.5, 3.0, 6.0, and 12.0 cpd; and in photopic conditions with no glare at 3.0, 6.0, 12.0. and 18.0 cpd. MRSE and monocular UCVA were assessed at those time points, and ease of lenticule removal was evaluated by surgeons.

Results : Mean pre-op mesopic CS without glare was 1.94, 2.06, 1.81, and 1.20 log units for 1.5, 3, 6, and 12 cpd, respectively. Mean pre-op mesopic CS with glare was 1.38, 1.61, 1.41, and 0.91 log units for 1.5, 3, 6, and 12 cpd, respectively. Mean pre-op photopic CS without glare was 2.29, 2.21, 1.82, and 1.33 log units for 3, 6, 12, and 18 cpd, respectively. Based on the 95% confidence interval of the median, there was no significant change in CS from pre-op to 3-mo (169 eyes available for analysis) or 6-mo (100 eyes) for any of the conditions measured. Mean MRSE was -0.33D at both the 3 and 6-mo post-op visits, and monocular UCVA/BSCVA was 20/20 or better for 86%/98% at 3-mo respectively, and 96%/100% of eyes at 6-mo post-operatively, respectively. In addition, surgeons rated lenticule removal as having no or mild adhesions in 87% of cases, with all other cases rated as moderate adhesions.

Conclusions : In this study, there was no significant change in CS after myopic refractive lenticule procedure at 3 and 6-months post-op. It is expected that with a nomogram adjustment.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

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