June 2023
Volume 64, Issue 8
Open Access
ARVO Annual Meeting Abstract  |   June 2023
Presbyopia: Understanding the biological contributions of Aging and Sex
Author Affiliations & Notes
  • Paul L Kaufman
    University of Wisconsin-Madison, Madison, Wisconsin, United States
  • Footnotes
    Commercial Relationships   Paul Kaufman None
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Investigative Ophthalmology & Visual Science June 2023, Vol.64, 4750. doi:
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      Paul L Kaufman; Presbyopia: Understanding the biological contributions of Aging and Sex . Invest. Ophthalmol. Vis. Sci. 2023;64(8):4750.

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      © ARVO (1962-2015); The Authors (2016-present)

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Abstract

Presentation Description : Presbyopia (old eye) defines the gradual age-related loss of visual accommodation (the ability to focus on near objects) as we age. It starts by approximately 20 years of age, by age 35 two-thirds are gone, by approximately age 40 becomes noticeable to the patient, and by approximately age 55 all is gone. Presbyopia is the most common ocular condition/disease worldwide, with an ‘attack rate’ of 100%. It is essentially gender neutral and no one is spared. There may be modest variations between different populations for various reasons, but essentially it is monotonously predictable. At present there is no biological therapeutic.Rhesus monkeys develop presbyopia on the same time scale relative to lifespan as humans, and the lenticular and extralenticular aspects of the accommodative apparatus are quite similar in the two species. Stay tuned.

This abstract was presented at the 2023 ARVO Annual Meeting, held in New Orleans, LA, April 23-27, 2023.

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